| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 32 | 32 | 12 | 12 | 3.41 | .289 | 1.20 | 8.0 | 2.9 | 9.5 | 235.0 | 208 | 100 | 89 | 26 | 75 | 248 | 8 | 0 | 0 | 2 | 21 | 4 | 3 | 3.34 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 31 | 31 | 12 | 15 | 5.16 | .328 | 1.45 | 10.0 | 3.1 | 7.9 | 193.2 | 215 | 118 | 111 | 34 | 66 | 169 | 0 | 0 | 0 | 0 | 15 | 2 | 6 | 4.60 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 30 | 30 | 10 | 11 | 4.96 | .333 | 1.46 | 10.1 | 3.2 | 8.2 | 188.2 | 210 | 111 | 104 | 41 | 66 | 171 | 1 | 0 | 0 | 0 | 14 | 7 | 1 | 5.18 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 30 | 30 | 12 | 11 | 4.28 | .316 | 1.37 | 9.4 | 3.0 | 4.3 | 197.2 | 205 | 103 | 94 | 22 | 66 | 94 | 7 | 0 | 0 | 1 | 15 | 3 | 1 | 4.55 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 30 | 29 | 13 | 12 | 4.56 | .319 | 1.38 | 8.7 | 3.7 | 6.6 | 195.1 | 189 | 105 | 99 | 18 | 81 | 143 | 3 | 0 | 1 | 0 | 15 | 4 | 8 | 4.04 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 81 | 87 | 0 | 1 | 2 | 2.30 | .282 | 1.18 | 7.2 | 3.4 | 8.0 | 82.1 | 66 | 22 | 21 | 3 | 31 | 73 | 0 | 3 | 2 | 0 | 0 | 0 | 5 | 2.83 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 76 | 52 | 0 | 4 | 2 | 2.61 | .304 | 1.30 | 7.9 | 3.9 | 8.1 | 58.2 | 51 | 17 | 17 | 3 | 25 | 52 | 0 | 1 | 1 | 0 | 0 | 1 | 4 | 3.22 |