| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 34 | 34 | 15 | 16 | 4.09 | .301 | 1.28 | 8.4 | 3.1 | 7.7 | 261.2 | 245 | 126 | 119 | 23 | 89 | 224 | 16 | 0 | 0 | 4 | 17 | 4 | 9 | 3.50 |
| SP | Brown, M.Brown, Mordecai # >> | 32 | 1908 | R | 85 | 33 | 33 | 14 | 17 | 3.99 | .282 | 1.17 | 8.1 | 2.5 | 4.0 | 252.1 | 226 | 119 | 112 | 21 | 69 | 111 | 10 | 0 | 0 | 2 | 20 | 3 | 6 | 4.06 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 32 | 32 | 11 | 18 | 5.08 | .314 | 1.35 | 9.5 | 2.7 | 4.5 | 228.1 | 240 | 133 | 129 | 19 | 69 | 113 | 5 | 0 | 0 | 0 | 10 | 4 | 5 | 4.05 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 32 | 32 | 13 | 13 | 5.54 | .319 | 1.38 | 10.2 | 2.3 | 4.3 | 217.2 | 245 | 142 | 134 | 18 | 56 | 104 | 4 | 0 | 0 | 0 | 13 | 5 | 5 | 3.96 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 31 | 31 | 16 | 13 | 4.70 | .337 | 1.51 | 9.4 | 4.2 | 6.3 | 210.2 | 220 | 118 | 110 | 25 | 98 | 146 | 1 | 0 | 0 | 0 | 16 | 3 | 4 | 4.60 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 46 | 0 | 2 | 3 | 4.70 | .349 | 1.59 | 10.9 | 3.5 | 7.6 | 51.2 | 62 | 27 | 27 | 2 | 20 | 43 | 0 | 7 | 3 | 0 | 0 | 1 | 5 | 3.06 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 34 | 0 | 3 | 3 | 4.47 | .308 | 1.34 | 9.2 | 2.9 | 7.0 | 46.1 | 47 | 23 | 23 | 7 | 15 | 36 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.39 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 1 | 0 | 0 | 0 | 0.00 | .222 | 0.86 | 0.0 | 9.0 | 0.0 | 2.1 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 14 | 0 | 1 | 0 | 6.30 | .355 | 1.65 | 11.7 | 3.2 | 5.0 | 20.0 | 26 | 14 | 14 | 3 | 7 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.90 |