| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 34 | 34 | 5 | 17 | 5.69 | .322 | 1.42 | 10.0 | 2.8 | 9.0 | 194.2 | 216 | 131 | 123 | 37 | 60 | 195 | 1 | 0 | 0 | 0 | 14 | 1 | 0 | 4.41 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 33 | 33 | 12 | 17 | 4.84 | .318 | 1.39 | 9.4 | 3.1 | 8.1 | 215.2 | 225 | 124 | 116 | 36 | 74 | 194 | 5 | 0 | 0 | 2 | 16 | 3 | 7 | 4.45 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 32 | 32 | 8 | 23 | 5.06 | .336 | 1.49 | 9.2 | 4.1 | 5.3 | 217.0 | 223 | 129 | 122 | 21 | 100 | 128 | 9 | 0 | 0 | 1 | 15 | 6 | 5 | 4.54 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 31 | 31 | 9 | 17 | 6.31 | .348 | 1.59 | 10.5 | 3.7 | 9.2 | 181.0 | 212 | 136 | 127 | 25 | 75 | 186 | 4 | 0 | 0 | 0 | 9 | 3 | 6 | 4.03 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 104 | 0 | 7 | 5 | 3.33 | .304 | 1.30 | 7.3 | 4.5 | 8.0 | 129.2 | 105 | 57 | 48 | 13 | 64 | 114 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.05 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 58 | 0 | 1 | 5 | 4.83 | .342 | 1.56 | 9.6 | 4.6 | 8.4 | 59.2 | 63 | 35 | 32 | 7 | 30 | 55 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 4.20 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 56 | 0 | 1 | 3 | 4.65 | .321 | 1.42 | 9.3 | 3.7 | 5.7 | 69.2 | 71 | 36 | 36 | 10 | 28 | 44 | 0 | 4 | 2 | 0 | 0 | 0 | 3 | 4.83 |