| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 95 | 12 | 12 | 4 | 6 | 3.52 | .311 | 1.32 | 9.4 | 2.5 | 5.3 | 87.0 | 91 | 34 | 34 | 7 | 24 | 51 | 3 | 0 | 0 | 2 | 7 | 3 | 1 | 3.80 |
| SP | Clement, M.Clement, Matt >> | 31 | 2005 | R | 42 | 11 | 11 | 3 | 5 | 5.61 | .310 | 1.30 | 8.5 | 3.2 | 6.1 | 59.1 | 56 | 39 | 37 | 11 | 21 | 40 | 0 | 0 | 0 | 0 | 3 | 3 | 2 | 5.29 |
| SP | Marquis, J.Marquis, Jason # >> | 27 | 2005 | R | 38 | 11 | 11 | 6 | 3 | 5.65 | .344 | 1.52 | 10.1 | 3.7 | 5.6 | 63.2 | 71 | 40 | 40 | 8 | 26 | 39 | 1 | 0 | 0 | 1 | 5 | 3 | 4 | 4.79 |
| SP | Towers, J.Towers, Josh >> | 28 | 2005 | R | 26 | 11 | 11 | 6 | 3 | 4.80 | .300 | 1.27 | 9.8 | 1.7 | 6.5 | 69.1 | 75 | 37 | 37 | 10 | 13 | 50 | 1 | 0 | 0 | 0 | 5 | 1 | 3 | 4.04 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 33 | 2005 | R | 72 | 27 | 0 | 2 | 1 | 2.82 | .286 | 1.20 | 7.3 | 3.6 | 7.1 | 38.1 | 31 | 12 | 12 | 2 | 15 | 30 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 3.29 |
| RP | Flores, R.Flores, Randy >> | 30 | 2005 | L | 53 | 22 | 0 | 4 | 1 | 7.27 | .376 | 1.81 | 11.1 | 5.2 | 8.7 | 26.0 | 32 | 21 | 21 | 5 | 15 | 25 | 0 | 3 | 3 | 0 | 0 | 0 | 1 | 5.31 |
| RP | Hasegawa, S.Hasegawa, Shigetoshi >> | 37 | 2005 | R | 38 | 21 | 0 | 1 | 0 | 3.12 | .278 | 1.15 | 8.3 | 2.1 | 4.5 | 26.0 | 24 | 9 | 9 | 1 | 6 | 13 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.19 |
| RP | Reitsma, C.Reitsma, Chris >> | 28 | 2005 | R | 27 | 16 | 0 | 0 | 0 | 2.61 | .271 | 1.06 | 7.2 | 2.7 | 6.3 | 20.2 | 16 | 8 | 6 | 2 | 6 | 14 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 3.95 |