| SP | Halladay, R.Halladay, Roy $ >> | 28 | 2005 | R | 95 | 22 | 22 | 10 | 8 | 4.09 | .304 | 1.30 | 9.4 | 2.3 | 5.7 | 134.1 | 140 | 67 | 61 | 15 | 34 | 85 | 3 | 0 | 0 | 0 | 13 | 2 | 2 | 3.99 |
| SP | Patterson, J.Patterson, John $ >> | 27 | 2005 | R | 86 | 22 | 22 | 8 | 9 | 4.50 | .331 | 1.47 | 9.8 | 3.4 | 6.3 | 134.0 | 146 | 71 | 67 | 16 | 51 | 94 | 0 | 0 | 0 | 0 | 13 | 2 | 4 | 4.34 |
| SP | Maddux, G.Maddux, Greg >> | 39 | 2005 | R | 47 | 20 | 19 | 8 | 9 | 6.01 | .361 | 1.66 | 11.8 | 3.2 | 5.6 | 97.1 | 127 | 66 | 65 | 15 | 35 | 60 | 0 | 0 | 0 | 0 | 7 | 3 | 1 | 4.95 |
| CL | Nathan, J.Nathan, Joe † $$ >> | 31 | 2005 | R | 97 | 46 | 0 | 3 | 3 | 1.98 | .265 | 1.04 | 6.5 | 2.9 | 8.5 | 50.0 | 36 | 11 | 11 | 5 | 16 | 47 | 0 | 21 | 0 | 0 | 0 | 2 | 1 | 3.50 |
| SU | Eyre, S.Eyre, Scott $$ >> | 33 | 2005 | L | 89 | 46 | 0 | 1 | 2 | 5.40 | .349 | 1.59 | 9.6 | 4.9 | 6.5 | 46.2 | 49 | 29 | 28 | 5 | 25 | 33 | 0 | 1 | 4 | 0 | 0 | 1 | 2 | 4.67 |
| RP | Carrasco, H.Carrasco, Hector >> | 36 | 2005 | R | 83 | 57 | 0 | 4 | 1 | 2.79 | .291 | 1.18 | 5.7 | 4.9 | 6.4 | 77.1 | 49 | 27 | 24 | 6 | 42 | 55 | 0 | 2 | 2 | 0 | 0 | 4 | 4 | 4.38 |
| RP | Thompson, B.Thompson, Brad >> | 23 | 2005 | R | 66 | 38 | 0 | 0 | 1 | 5.57 | .351 | 1.60 | 11.1 | 3.2 | 4.1 | 42.0 | 52 | 27 | 26 | 6 | 15 | 19 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 5.10 |