| SP | Willis, D.Willis, Dontrelle $ >> | 23 | 2005 | L | 87 | 22 | 22 | 8 | 8 | 3.74 | .305 | 1.29 | 9.4 | 2.3 | 6.4 | 151.2 | 158 | 65 | 63 | 16 | 38 | 107 | 2 | 0 | 0 | 2 | 14 | 4 | 0 | 3.79 |
| RP | Valverde, J.Valverde, Jose >> | 26 | 2005 | R | 84 | 49 | 0 | 3 | 3 | 2.43 | .259 | 1.02 | 6.7 | 2.4 | 9.1 | 63.0 | 47 | 17 | 17 | 8 | 17 | 64 | 0 | 3 | 0 | 0 | 0 | 2 | 4 | 3.52 |
| RP | Heilman, A.Heilman, Aaron >> | 27 | 2005 | R | 71 | 45 | 0 | 3 | 7 | 4.43 | .330 | 1.46 | 10.2 | 3.0 | 6.4 | 67.0 | 76 | 36 | 33 | 12 | 22 | 48 | 0 | 5 | 4 | 0 | 0 | 1 | 0 | 4.93 |
| RP | Santana, J.Santana, Julio >> | 32 | 2005 | R | 57 | 31 | 0 | 5 | 0 | 2.52 | .258 | 1.02 | 6.2 | 3.0 | 10.2 | 39.1 | 27 | 12 | 11 | 2 | 13 | 44 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 2.49 |
| SP | Beckett, J.Beckett, Josh >> | 25 | 2005 | R | 88 | 8 | 0 | 1 | 2 | 5.56 | .346 | 1.59 | 9.8 | 4.9 | 6.5 | 11.1 | 12 | 7 | 7 | 1 | 6 | 8 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.36 |