| SP | Martinez, P.Martinez, Pedro >> | 34 | 2005 | R | 100 | 11 | 11 | 5 | 2 | 1.56 | .273 | 1.07 | 7.0 | 2.7 | 8.1 | 80.2 | 62 | 18 | 14 | 4 | 24 | 72 | 2 | 0 | 0 | 1 | 9 | 5 | 1 | 2.94 |
| SP | Colon, B.Colon, Bartolo >> | 32 | 2005 | R | 80 | 11 | 11 | 4 | 4 | 4.85 | .346 | 1.56 | 11.0 | 3.2 | 5.8 | 68.2 | 83 | 39 | 37 | 10 | 24 | 44 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 4.76 |
| SP | Oswalt, R.Oswalt, Roy # >> | 28 | 2005 | R | 71 | 11 | 11 | 5 | 3 | 4.35 | .300 | 1.22 | 9.1 | 1.9 | 6.5 | 72.1 | 73 | 35 | 35 | 12 | 15 | 52 | 0 | 0 | 0 | 0 | 6 | 5 | 2 | 4.56 |
| SP | Harang, A.Harang, Aaron >> | 27 | 2005 | R | 51 | 11 | 11 | 2 | 4 | 7.04 | .365 | 1.67 | 12.1 | 2.9 | 5.6 | 55.0 | 74 | 46 | 43 | 9 | 18 | 34 | 0 | 0 | 0 | 0 | 3 | 3 | 1 | 5.04 |
| SU | Wheeler, D.Wheeler, Dan >> | 28 | 2005 | R | 90 | 15 | 0 | 1 | 0 | 1.93 | .282 | 1.18 | 9.5 | 1.5 | 7.0 | 18.2 | 19 | 4 | 4 | 0 | 3 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1.94 |
| RP | Street, H.Street, Huston $ >> | 22 | 2005 | R | 91 | 28 | 0 | 2 | 3 | 2.88 | .285 | 1.17 | 7.1 | 3.4 | 6.4 | 34.1 | 27 | 12 | 11 | 3 | 13 | 24 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 3.97 |
| RP | Rincon, J.Rincon, Juan >> | 26 | 2005 | R | 67 | 20 | 0 | 2 | 1 | 4.42 | .360 | 1.58 | 11.5 | 3.0 | 10.5 | 18.1 | 23 | 9 | 9 | 3 | 6 | 21 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 4.17 |
| RP | Fuentes, B.Fuentes, Brian >> | 30 | 2005 | L | 63 | 29 | 0 | 1 | 0 | 4.43 | .323 | 1.43 | 8.6 | 4.5 | 8.2 | 22.1 | 21 | 11 | 11 | 3 | 11 | 20 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 4.45 |
| RP | Rodriguez, F.Rodriguez, Francisco $ >> | 23 | 2005 | R | 79 | 20 | 0 | 2 | 0 | 5.85 | .286 | 1.20 | 9.5 | 1.4 | 8.6 | 20.0 | 21 | 13 | 13 | 8 | 3 | 19 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 6.75 |
| RP | Cordero, F.Cordero, Francisco >> | 30 | 2005 | R | 45 | 21 | 0 | 3 | 0 | 5.29 | .346 | 1.53 | 9.0 | 4.8 | 10.6 | 17.0 | 17 | 10 | 10 | 1 | 9 | 20 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.18 |
| RP | Hernandez, R.Hernandez, Roberto >> | 41 | 2005 | R | 56 | 14 | 0 | 0 | 1 | 6.28 | .377 | 1.81 | 11.6 | 5.1 | 8.4 | 14.1 | 18 | 10 | 10 | 1 | 8 | 13 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.79 |