| SP | Mussina, M.Mussina, Mike >> | 35 | 2003 | R | 88 | 23 | 23 | 5 | 10 | 4.87 | .347 | 1.56 | 10.7 | 3.3 | 7.3 | 135.0 | 160 | 79 | 73 | 20 | 50 | 110 | 1 | 0 | 0 | 0 | 10 | 5 | 3 | 4.52 |
| SP | Padilla, V.Padilla, Vicente >> | 26 | 2003 | R | 68 | 23 | 23 | 2 | 12 | 5.92 | .371 | 1.72 | 11.5 | 4.1 | 5.5 | 124.2 | 159 | 91 | 82 | 25 | 56 | 76 | 0 | 0 | 0 | 0 | 9 | 6 | 1 | 5.90 |
| SP | Washburn, J.Washburn, Jarrod # >> | 29 | 2003 | L | 54 | 22 | 22 | 7 | 9 | 5.78 | .340 | 1.51 | 10.7 | 3.0 | 6.5 | 113.2 | 134 | 82 | 73 | 24 | 38 | 82 | 0 | 0 | 0 | 0 | 9 | 4 | 4 | 5.42 |
| SP | Sheets, B.Sheets, Ben # >> | 25 | 2003 | R | 50 | 22 | 22 | 10 | 7 | 4.67 | .345 | 1.55 | 10.4 | 3.6 | 6.2 | 131.0 | 151 | 77 | 68 | 22 | 52 | 90 | 0 | 0 | 0 | 0 | 12 | 4 | 4 | 5.09 |
| SP | Zambrano, V.Zambrano, Victor >> | 28 | 2003 | R | 33 | 22 | 22 | 6 | 8 | 5.64 | .333 | 1.47 | 8.1 | 5.2 | 6.7 | 105.1 | 94 | 67 | 66 | 5 | 61 | 78 | 0 | 0 | 0 | 0 | 5 | 3 | 7 | 3.96 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 90 | 64 | 0 | 3 | 3 | 4.58 | .309 | 1.33 | 7.2 | 4.9 | 8.6 | 70.2 | 56 | 37 | 36 | 8 | 38 | 67 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.24 |
| RP | Schoeneweis, S.Schoeneweis, Scott >> | 30 | 2003 | L | 40 | 60 | 0 | 3 | 3 | 4.40 | .330 | 1.44 | 9.5 | 3.6 | 7.5 | 73.2 | 77 | 36 | 36 | 6 | 29 | 61 | 0 | 4 | 5 | 0 | 0 | 3 | 6 | 3.71 |
| SP | Suppan, J.Suppan, Jeff >> | 28 | 2003 | R | 24 | 4 | 0 | 0 | 0 | 13.50 | .471 | 2.67 | 18.0 | 6.0 | 1.5 | 6.0 | 12 | 9 | 9 | 3 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.17 |
| SP | Pettitte, A.Pettitte, Andy >> | 31 | 2003 | L | 22 | 51 | 0 | 3 | 9 | 6.35 | .372 | 1.78 | 11.5 | 4.6 | 6.5 | 79.1 | 101 | 58 | 56 | 13 | 40 | 57 | 0 | 8 | 2 | 0 | 0 | 0 | 4 | 5.22 |