| SP | Santana, J.Santana, Johan >> | 24 | 2003 | L | 97 | 14 | 14 | 1 | 3 | 5.84 | .368 | 1.72 | 11.0 | 4.6 | 10.1 | 49.1 | 60 | 32 | 32 | 6 | 25 | 55 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.94 |
| SP | Gonzalez, G.Gonzalez, Geremi >> | 28 | 2003 | R | 65 | 14 | 14 | 5 | 4 | 4.81 | .316 | 1.38 | 8.0 | 4.4 | 5.1 | 88.0 | 78 | 47 | 47 | 9 | 43 | 50 | 0 | 0 | 0 | 0 | 7 | 1 | 1 | 4.69 |
| SP | Penny, B.Penny, Brad # >> | 25 | 2003 | R | 44 | 14 | 14 | 6 | 5 | 4.78 | .349 | 1.59 | 10.8 | 3.6 | 7.0 | 84.2 | 101 | 46 | 45 | 10 | 34 | 65 | 0 | 0 | 0 | 0 | 7 | 1 | 2 | 4.25 |
| SP | Stephenson, G.Stephenson, Garrett >> | 31 | 2003 | R | 36 | 13 | 13 | 3 | 6 | 6.64 | .374 | 1.74 | 12.3 | 3.6 | 3.9 | 63.2 | 86 | 51 | 47 | 10 | 25 | 27 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 5.54 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 21 | 2003 | R | 95 | 34 | 0 | 2 | 1 | 4.07 | .274 | 1.13 | 5.6 | 4.7 | 8.4 | 48.2 | 30 | 23 | 22 | 7 | 25 | 45 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 4.58 |
| RP | Rivera, M.Rivera, Mariano >> | 34 | 2003 | R | 75 | 36 | 0 | 5 | 4 | 4.30 | .270 | 1.11 | 8.1 | 1.9 | 7.1 | 52.1 | 47 | 25 | 25 | 8 | 11 | 41 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 4.06 |
| RP | Bradford, C.Bradford, Chad >> | 29 | 2003 | R | 48 | 33 | 0 | 1 | 2 | 2.98 | .295 | 1.21 | 6.8 | 4.2 | 6.6 | 45.1 | 34 | 16 | 15 | 4 | 21 | 33 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 4.22 |
| RP | Rincon, J.Rincon, Juan >> | 24 | 2003 | R | 38 | 32 | 0 | 1 | 2 | 3.63 | .287 | 1.21 | 7.8 | 3.3 | 8.0 | 44.2 | 38 | 18 | 18 | 6 | 16 | 39 | 0 | 4 | 0 | 0 | 0 | 0 | 4 | 4.09 |
| RP | Speier, J.Speier, Justin >> | 30 | 2003 | R | 28 | 25 | 0 | 0 | 1 | 6.12 | .359 | 1.60 | 9.7 | 4.7 | 4.3 | 25.0 | 27 | 18 | 17 | 2 | 13 | 12 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 4.88 |
| SP | Buehrle, M.Buehrle, Mark >> | 24 | 2003 | L | 12 | 2 | 0 | 0 | 0 | 9.00 | .250 | 1.00 | 9.0 | 0.0 | 9.0 | 1.0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 14.00 |
| SP | Suppan, J.Suppan, Jeff >> | 28 | 2003 | R | 24 | 12 | 0 | 4 | 1 | 3.44 | .329 | 1.41 | 10.1 | 2.6 | 4.8 | 34.0 | 38 | 13 | 13 | 2 | 10 | 18 | 0 | 1 | 1 | 0 | 0 | 2 | 2 | 3.76 |