| SP | Sanchez, J.Sanchez, Jonathan # $$ >> | 30 | 2010 | L | 52 | 17 | 17 | 6 | 9 | 4.78 | .313 | 1.32 | 7.5 | 4.4 | 8.8 | 96.0 | 80 | 52 | 51 | 14 | 47 | 94 | 0 | 0 | 0 | 0 | 6 | 4 | 3 | 4.53 |
| SP | Maine, J.Maine, John $$ >> | 31 | 2007 | R | 49 | 17 | 17 | 5 | 8 | 3.97 | .298 | 1.27 | 7.6 | 3.9 | 6.8 | 113.1 | 95 | 58 | 50 | 12 | 49 | 86 | 0 | 0 | 0 | 0 | 10 | 0 | 2 | 4.16 |
| SP | Lincecum, T.Lincecum, Tim $$ >> | 28 | 2010 | R | 51 | 16 | 16 | 2 | 9 | 4.31 | .305 | 1.30 | 8.4 | 3.4 | 8.0 | 110.2 | 103 | 64 | 53 | 17 | 41 | 98 | 0 | 0 | 0 | 0 | 8 | 2 | 3 | 4.40 |
| SP | Matsuzaka, D.Matsuzaka, Daisuke $ >> | 32 | 2008 | R | 31 | 16 | 16 | 4 | 9 | 5.06 | .337 | 1.49 | 8.6 | 4.8 | 7.1 | 80.0 | 76 | 58 | 45 | 19 | 43 | 63 | 0 | 0 | 0 | 0 | 5 | 3 | 2 | 6.24 |
| SP | Francis, J.Francis, Jeff $ >> | 31 | 2004 | L | 39 | 11 | 10 | 2 | 7 | 6.82 | .326 | 1.45 | 10.2 | 3.0 | 5.7 | 60.2 | 68 | 49 | 46 | 9 | 20 | 38 | 1 | 0 | 0 | 0 | 2 | 0 | 1 | 4.68 |
| RP | Zumaya, J.Zumaya, Joel $$ >> | 28 | 2006 | R | 90 | 43 | 0 | 2 | 1 | 2.88 | .247 | 0.96 | 6.4 | 2.3 | 10.0 | 84.1 | 60 | 28 | 27 | 11 | 21 | 93 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 3.31 |
| RP | Masset, N.Masset, Nick $$ >> | 30 | 2009 | R | 62 | 37 | 0 | 0 | 1 | 4.81 | .263 | 1.07 | 8.4 | 1.3 | 9.8 | 48.2 | 45 | 26 | 26 | 11 | 7 | 52 | 0 | 2 | 3 | 0 | 0 | 0 | 2 | 4.25 |
| RP | Lidge, B.Lidge, Brad # $ >> | 36 | 2004 | R | 25 | 28 | 0 | 3 | 3 | 5.53 | .366 | 1.73 | 11.0 | 5.0 | 8.3 | 27.2 | 33 | 26 | 17 | 6 | 15 | 25 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.70 |
| RP | Hanrahan, J.Hanrahan, Joel $$ >> | 31 | 2010 | R | 33 | 22 | 0 | 0 | 1 | 3.32 | .278 | 1.16 | 5.7 | 4.7 | 13.3 | 19.0 | 12 | 14 | 7 | 2 | 10 | 28 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 3.00 |
| RP | Villanueva, C.Villanueva, Carlos $ >> | 29 | 2011 | R | 13 | 21 | 0 | 1 | 3 | 5.11 | .323 | 1.43 | 7.5 | 5.4 | 5.6 | 37.0 | 31 | 26 | 21 | 7 | 22 | 23 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 6.00 |
| SP | De La Rosa, J.De La Rosa, Jorge $$ >> | 31 | 2009 | L | 20 | 7 | 0 | 0 | 0 | 5.40 | .324 | 1.38 | 7.9 | 5.1 | 10.1 | 16.2 | 14 | 10 | 10 | 5 | 9 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.69 |