| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 30 | 30 | 19 | 2 | 2.32 | .233 | 0.88 | 6.3 | 1.7 | 11.1 | 205.2 | 143 | 55 | 53 | 21 | 38 | 252 | 2 | 0 | 0 | 1 | 25 | 6 | 0 | 2.52 |
| SP | Snell, B.Snell, Blake † $ >> | 25 | 2018 | L | 88 | 31 | 31 | 18 | 3 | 2.50 | .257 | 1.03 | 6.0 | 3.3 | 9.0 | 205.1 | 136 | 60 | 57 | 20 | 75 | 204 | 1 | 0 | 0 | 0 | 23 | 2 | 3 | 3.40 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 87 | 30 | 30 | 12 | 5 | 3.82 | .272 | 1.09 | 7.5 | 2.3 | 5.7 | 172.0 | 144 | 76 | 73 | 19 | 44 | 108 | 2 | 0 | 0 | 1 | 15 | 5 | 6 | 4.03 |
| SP | Harden, R.Harden, Rich $ >> | 27 | 2008 | R | 68 | 29 | 29 | 18 | 6 | 3.20 | .287 | 1.18 | 6.6 | 4.1 | 8.7 | 185.2 | 135 | 68 | 66 | 21 | 84 | 178 | 1 | 0 | 0 | 1 | 18 | 5 | 1 | 3.99 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 70 | 34 | 0 | 3 | 0 | 0.71 | .208 | 0.79 | 4.5 | 2.6 | 9.9 | 38.0 | 19 | 3 | 3 | 0 | 11 | 42 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 1.66 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 25 | 0 | 1 | 1 | 1.37 | .288 | 1.22 | 7.3 | 3.8 | 10.0 | 26.1 | 21 | 4 | 4 | 2 | 11 | 29 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 3.04 |
| RP | Chapman, A.Chapman, Aroldis # >> | 37 | 2025 | L | 96 | 62 | 0 | 3 | 0 | 4.71 | .283 | 1.19 | 6.8 | 3.9 | 10.1 | 57.1 | 43 | 30 | 30 | 12 | 25 | 64 | 0 | 4 | 3 | 0 | 0 | 0 | 4 | 4.81 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 57 | 10 | 1 | 5 | 0 | 2.26 | .269 | 1.06 | 7.2 | 2.5 | 6.4 | 51.2 | 41 | 14 | 13 | 5 | 14 | 36 | 0 | 0 | 0 | 0 | 1 | 2 | 4 | 3.80 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 60 | 0 | 5 | 10 | 3.06 | .280 | 1.15 | 8.0 | 2.5 | 8.4 | 61.2 | 54 | 23 | 21 | 8 | 17 | 57 | 0 | 37 | 4 | 0 | 0 | 1 | 0 | 3.72 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 55 | 27 | 0 | 2 | 1 | 3.86 | .317 | 1.36 | 6.8 | 5.5 | 9.3 | 28.0 | 21 | 12 | 12 | 3 | 17 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.25 |