| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 31 | 31 | 11 | 16 | 3.87 | .300 | 1.25 | 8.4 | 2.9 | 9.9 | 214.0 | 199 | 99 | 92 | 22 | 68 | 235 | 9 | 0 | 0 | 2 | 17 | 8 | 4 | 3.21 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 84 | 31 | 31 | 8 | 11 | 5.72 | .319 | 1.40 | 9.1 | 3.6 | 8.3 | 151.0 | 152 | 101 | 96 | 18 | 60 | 140 | 0 | 0 | 0 | 0 | 11 | 0 | 7 | 3.89 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 30 | 30 | 10 | 7 | 5.11 | .321 | 1.40 | 9.2 | 3.4 | 7.9 | 185.0 | 189 | 110 | 105 | 35 | 70 | 162 | 3 | 0 | 0 | 0 | 14 | 3 | 5 | 4.89 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 30 | 30 | 14 | 10 | 4.05 | .305 | 1.30 | 8.4 | 3.4 | 6.1 | 195.2 | 181 | 93 | 88 | 20 | 74 | 132 | 4 | 0 | 0 | 2 | 17 | 2 | 5 | 4.15 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 65 | 30 | 28 | 6 | 9 | 4.43 | .305 | 1.30 | 9.8 | 1.9 | 9.9 | 182.2 | 198 | 103 | 90 | 25 | 39 | 201 | 2 | 0 | 0 | 1 | 14 | 4 | 4 | 3.29 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 79 | 75 | 0 | 5 | 9 | 2.00 | .251 | 0.99 | 5.9 | 3.1 | 10.3 | 94.2 | 62 | 26 | 21 | 6 | 32 | 108 | 0 | 10 | 2 | 0 | 0 | 1 | 2 | 2.59 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 77 | 50 | 0 | 4 | 3 | 2.59 | .278 | 1.14 | 6.3 | 4.0 | 7.5 | 59.0 | 41 | 19 | 17 | 6 | 26 | 49 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 4.03 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 65 | 35 | 0 | 3 | 2 | 2.48 | .302 | 1.25 | 8.1 | 3.2 | 7.9 | 40.0 | 36 | 12 | 11 | 3 | 14 | 35 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.43 |
| SP | DeLeon, J.DeLeon, Jose >> | 29 | 1989 | R | 58 | 10 | 0 | 1 | 1 | 2.37 | .240 | 0.89 | 5.7 | 2.4 | 6.6 | 19.0 | 12 | 5 | 5 | 1 | 5 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.16 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 62 | 22 | 0 | 0 | 1 | 3.80 | .402 | 2.02 | 9.9 | 8.6 | 12.4 | 21.1 | 23 | 9 | 9 | 1 | 20 | 29 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.71 |