| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 25 | 25 | 10 | 6 | 2.77 | .269 | 1.09 | 7.5 | 2.3 | 8.0 | 166.0 | 139 | 54 | 51 | 17 | 42 | 148 | 0 | 0 | 0 | 0 | 20 | 2 | 0 | 3.34 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 24 | 24 | 3 | 11 | 7.40 | .363 | 1.68 | 11.8 | 3.3 | 8.3 | 121.2 | 159 | 102 | 100 | 25 | 45 | 112 | 0 | 0 | 0 | 0 | 7 | 4 | 2 | 5.05 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 23 | 22 | 6 | 6 | 4.50 | .310 | 1.34 | 8.3 | 3.7 | 5.5 | 136.0 | 126 | 71 | 68 | 25 | 56 | 83 | 5 | 0 | 0 | 2 | 8 | 1 | 2 | 5.43 |
| RP | Nathan, J.Nathan, Joe † >> | 32 | 2006 | R | 87 | 75 | 0 | 6 | 6 | 2.63 | .276 | 1.10 | 6.6 | 3.3 | 9.1 | 89.0 | 65 | 30 | 26 | 8 | 33 | 90 | 0 | 11 | 3 | 0 | 0 | 4 | 3 | 3.39 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 44 | 0 | 2 | 2 | 4.22 | .304 | 1.29 | 7.3 | 4.4 | 10.2 | 53.1 | 43 | 25 | 25 | 9 | 26 | 60 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 4.47 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 38 | 0 | 2 | 3 | 5.06 | .326 | 1.43 | 9.0 | 4.1 | 6.4 | 42.2 | 42 | 25 | 24 | 6 | 19 | 30 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 4.86 |