| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 26 | 26 | 7 | 8 | 3.84 | .297 | 1.23 | 8.5 | 2.6 | 7.6 | 143.0 | 135 | 62 | 61 | 16 | 41 | 121 | 0 | 0 | 0 | 0 | 12 | 5 | 2 | 3.73 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 24 | 24 | 10 | 8 | 3.40 | .277 | 1.13 | 8.0 | 2.2 | 4.4 | 166.2 | 148 | 68 | 63 | 13 | 40 | 82 | 2 | 0 | 0 | 2 | 16 | 4 | 4 | 3.83 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 80 | 23 | 23 | 9 | 6 | 3.95 | .278 | 1.15 | 5.8 | 4.5 | 7.4 | 134.1 | 87 | 65 | 59 | 18 | 67 | 110 | 0 | 0 | 0 | 0 | 12 | 1 | 8 | 4.63 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 23 | 23 | 6 | 10 | 4.89 | .316 | 1.39 | 8.5 | 4.0 | 7.8 | 143.2 | 135 | 79 | 78 | 23 | 64 | 124 | 1 | 0 | 0 | 0 | 11 | 0 | 2 | 4.70 |
| SP | McDowell, S.McDowell, Sam # >> | 26 | 1968 | L | 45 | 22 | 21 | 8 | 4 | 3.85 | .275 | 1.12 | 6.7 | 3.5 | 7.7 | 135.2 | 100 | 58 | 58 | 20 | 52 | 116 | 0 | 0 | 0 | 0 | 10 | 2 | 3 | 4.41 |
| RP | Miller, A.Miller, Andrew † >> | 29 | 2014 | L | 88 | 61 | 0 | 8 | 2 | 2.28 | .235 | 0.92 | 6.0 | 2.3 | 9.5 | 79.0 | 53 | 20 | 20 | 8 | 20 | 83 | 0 | 7 | 5 | 0 | 0 | 0 | 2 | 2.97 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 46 | 0 | 5 | 4 | 1.95 | .276 | 1.13 | 6.3 | 4.0 | 8.1 | 50.2 | 35 | 12 | 11 | 2 | 22 | 45 | 0 | 10 | 2 | 0 | 0 | 1 | 3 | 3.10 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 38 | 0 | 4 | 2 | 4.79 | .337 | 1.48 | 6.6 | 6.8 | 10.8 | 41.1 | 30 | 22 | 22 | 4 | 31 | 49 | 0 | 7 | 3 | 0 | 0 | 2 | 1 | 4.29 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 18 | 0 | 1 | 0 | 2.04 | .232 | 0.91 | 5.8 | 2.6 | 7.4 | 17.2 | 11 | 4 | 4 | 1 | 5 | 14 | 0 | 5 | 1 | 0 | 0 | 0 | 1 | 3.00 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 23 | 0 | 5 | 0 | 2.65 | .261 | 0.99 | 6.2 | 2.8 | 7.4 | 57.2 | 39 | 19 | 17 | 4 | 18 | 47 | 0 | 0 | 0 | 0 | 0 | 4 | 2 | 3.42 |