| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 94 | 18 | 18 | 9 | 4 | 3.80 | .289 | 1.21 | 8.1 | 2.9 | 5.5 | 132.2 | 119 | 59 | 56 | 12 | 42 | 80 | 4 | 0 | 0 | 2 | 10 | 1 | 3 | 3.95 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 16 | 16 | 3 | 9 | 5.50 | .365 | 1.71 | 9.4 | 6.2 | 9.1 | 73.2 | 76 | 48 | 45 | 6 | 50 | 74 | 0 | 0 | 0 | 0 | 2 | 1 | 2 | 4.14 |
| RP | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 46 | 0 | 6 | 1 | 3.39 | .269 | 1.09 | 7.0 | 2.7 | 10.4 | 69.0 | 54 | 29 | 26 | 11 | 21 | 80 | 0 | 7 | 0 | 0 | 0 | 1 | 1 | 3.71 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 42 | 0 | 5 | 4 | 3.92 | .284 | 1.18 | 8.8 | 1.8 | 5.5 | 78.0 | 76 | 37 | 34 | 15 | 16 | 48 | 0 | 6 | 3 | 0 | 0 | 1 | 4 | 4.92 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 49 | 24 | 0 | 2 | 3 | 6.43 | .417 | 2.11 | 13.2 | 5.8 | 5.8 | 28.0 | 41 | 21 | 20 | 5 | 18 | 18 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 6.07 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 50 | 16 | 1 | 1 | 3 | 5.15 | .329 | 1.45 | 12.3 | 1.0 | 9.3 | 36.2 | 49 | 22 | 21 | 3 | 4 | 37 | 1 | 2 | 0 | 0 | 1 | 1 | 0 | 2.44 |