| SP | Martinez, P.Martinez, Pedro # $$ >> | 29 | 2000 | R | 100 | 33 | 33 | 12 | 14 | 3.37 | .257 | 1.02 | 7.6 | 1.7 | 9.0 | 232.2 | 195 | 97 | 87 | 22 | 43 | 231 | 10 | 0 | 0 | 4 | 21 | 3 | 1 | 2.84 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 31 | 31 | 10 | 10 | 4.45 | .317 | 1.37 | 7.7 | 4.6 | 3.9 | 194.1 | 167 | 109 | 96 | 19 | 100 | 84 | 4 | 0 | 0 | 2 | 16 | 3 | 1 | 5.00 |
| SP | McQuillan, G.McQuillan, George >> | 23 | 1908 | R | 48 | 18 | 18 | 7 | 7 | 2.65 | .268 | 1.07 | 6.3 | 3.4 | 4.0 | 125.2 | 88 | 46 | 37 | 9 | 47 | 55 | 1 | 0 | 0 | 1 | 13 | 3 | 3 | 4.26 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 29 | 27 | 9 | 9 | 5.65 | .335 | 1.50 | 10.3 | 3.2 | 5.9 | 173.2 | 198 | 121 | 109 | 25 | 62 | 113 | 5 | 0 | 0 | 0 | 10 | 3 | 5 | 4.70 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 70 | 0 | 8 | 11 | 3.45 | .305 | 1.30 | 6.8 | 4.9 | 7.4 | 73.0 | 55 | 28 | 28 | 6 | 40 | 60 | 0 | 33 | 8 | 0 | 0 | 1 | 0 | 4.11 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 83 | 75 | 0 | 5 | 0 | 4.20 | .291 | 1.21 | 6.8 | 4.1 | 4.7 | 90.0 | 68 | 47 | 42 | 14 | 41 | 47 | 0 | 0 | 4 | 0 | 0 | 2 | 0 | 5.41 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 43 | 0 | 4 | 1 | 2.36 | .271 | 1.09 | 7.0 | 3.0 | 9.2 | 45.2 | 35 | 13 | 12 | 2 | 15 | 46 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 2.60 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 32 | 0 | 0 | 0 | 3.23 | .295 | 1.26 | 6.7 | 4.6 | 9.0 | 39.0 | 29 | 18 | 14 | 4 | 20 | 39 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 3.87 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 32 | 0 | 1 | 1 | 1.93 | .277 | 1.10 | 5.6 | 4.4 | 9.2 | 37.1 | 23 | 13 | 8 | 2 | 18 | 38 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 3.27 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 15 | 0 | 0 | 0 | 3.18 | .363 | 1.65 | 9.0 | 5.8 | 6.9 | 17.0 | 17 | 7 | 6 | 1 | 11 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.35 |
| SP | Newhouser, H.Newhouser, Hal >> | 25 | 1946 | L | 32 | 13 | 1 | 3 | 3 | 5.44 | .351 | 1.60 | 9.4 | 5.1 | 5.3 | 48.0 | 50 | 34 | 29 | 5 | 27 | 28 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.94 |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 53 | 4 | 3 | 1 | 2 | 5.40 | .286 | 1.20 | 9.0 | 2.0 | 5.5 | 18.1 | 18 | 11 | 11 | 1 | 4 | 11 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 3.17 |