| SP | McNally, D.McNally, Dave † >> | 26 | 1968 | L | 96 | 31 | 31 | 13 | 13 | 3.70 | .278 | 1.15 | 7.6 | 2.8 | 5.1 | 235.2 | 198 | 101 | 97 | 23 | 73 | 132 | 11 | 0 | 0 | 2 | 15 | 1 | 6 | 4.09 |
| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 74 | 31 | 31 | 12 | 15 | 4.85 | .330 | 1.47 | 9.3 | 3.8 | 5.4 | 206.0 | 214 | 123 | 111 | 22 | 88 | 124 | 8 | 0 | 0 | 0 | 13 | 3 | 2 | 4.51 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 31 | 31 | 10 | 14 | 5.57 | .325 | 1.41 | 9.3 | 3.4 | 7.9 | 181.0 | 187 | 119 | 112 | 30 | 69 | 159 | 5 | 0 | 0 | 4 | 13 | 5 | 4 | 4.62 |
| SP | Caldwell, R.Caldwell, Ray # >> | 26 | 1914 | R | 63 | 31 | 31 | 7 | 13 | 5.81 | .349 | 1.58 | 10.6 | 3.6 | 3.8 | 176.2 | 208 | 125 | 114 | 22 | 71 | 74 | 0 | 0 | 0 | 0 | 12 | 5 | 3 | 5.08 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 30 | 30 | 9 | 10 | 5.38 | .332 | 1.45 | 10.0 | 3.1 | 6.0 | 170.2 | 189 | 105 | 102 | 21 | 59 | 113 | 0 | 0 | 0 | 0 | 11 | 6 | 5 | 4.42 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 75 | 0 | 4 | 3 | 3.69 | .297 | 1.24 | 7.0 | 4.2 | 8.7 | 129.1 | 101 | 63 | 53 | 13 | 60 | 124 | 0 | 5 | 4 | 0 | 0 | 3 | 0 | 3.85 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 75 | 0 | 6 | 4 | 4.61 | .310 | 1.31 | 7.6 | 4.3 | 5.8 | 93.2 | 79 | 53 | 48 | 11 | 44 | 60 | 0 | 7 | 5 | 0 | 0 | 3 | 0 | 4.76 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 52 | 0 | 4 | 5 | 2.14 | .281 | 1.14 | 5.4 | 4.9 | 8.9 | 63.0 | 38 | 17 | 15 | 4 | 34 | 62 | 0 | 3 | 2 | 0 | 0 | 2 | 0 | 3.57 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 45 | 0 | 1 | 3 | 3.66 | .262 | 1.07 | 8.1 | 1.5 | 7.7 | 71.1 | 64 | 33 | 29 | 9 | 12 | 61 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 3.44 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 47 | 20 | 1 | 2 | 4 | 8.13 | .421 | 2.16 | 17.2 | 2.4 | 4.5 | 34.1 | 65 | 33 | 31 | 9 | 9 | 17 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 6.32 |