| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 23 | 23 | 7 | 9 | 5.02 | .319 | 1.39 | 8.3 | 4.2 | 8.2 | 138.0 | 128 | 78 | 77 | 21 | 64 | 126 | 1 | 0 | 0 | 0 | 12 | 2 | 3 | 4.59 |
| SP | Arrieta, J.Arrieta, Jake † # >> | 29 | 2015 | R | 93 | 23 | 23 | 13 | 5 | 2.77 | .278 | 1.15 | 7.9 | 2.4 | 7.4 | 172.0 | 151 | 57 | 53 | 13 | 46 | 142 | 2 | 0 | 0 | 0 | 18 | 2 | 3 | 3.17 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 17 | 17 | 4 | 8 | 5.20 | .327 | 1.42 | 10.0 | 2.8 | 7.4 | 119.1 | 132 | 75 | 69 | 19 | 37 | 98 | 3 | 0 | 0 | 1 | 6 | 5 | 3 | 4.49 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 49 | 38 | 0 | 2 | 1 | 3.20 | .269 | 1.11 | 7.2 | 2.9 | 7.9 | 25.1 | 20 | 10 | 9 | 2 | 8 | 22 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.24 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 40 | 0 | 7 | 2 | 3.71 | .261 | 1.03 | 7.1 | 2.1 | 9.3 | 34.0 | 27 | 15 | 14 | 5 | 8 | 35 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.65 |
| CL | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 30 | 0 | 4 | 1 | 2.42 | .250 | 1.00 | 5.9 | 3.1 | 9.3 | 26.0 | 17 | 7 | 7 | 2 | 9 | 27 | 0 | 15 | 3 | 0 | 0 | 0 | 0 | 2.96 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 34 | 0 | 1 | 2 | 4.65 | .301 | 1.26 | 9.9 | 1.5 | 10.2 | 31.0 | 34 | 19 | 16 | 11 | 5 | 35 | 0 | 17 | 4 | 0 | 0 | 1 | 0 | 5.94 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 19 | 0 | 0 | 3 | 6.46 | .361 | 1.70 | 10.8 | 4.8 | 4.8 | 15.1 | 18 | 12 | 11 | 6 | 8 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 8.73 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 9 | 5 | 5 | 1 | 5.27 | .347 | 1.58 | 11.6 | 2.7 | 4.0 | 56.1 | 72 | 35 | 33 | 5 | 17 | 25 | 0 | 0 | 0 | 0 | 4 | 1 | 2 | 4.23 |