| SP | Scherzer, M.Scherzer, Max $ >> | 30 | 2008 | R | 99 | 22 | 22 | 6 | 10 | 5.02 | .313 | 1.35 | 10.0 | 2.2 | 7.5 | 141.2 | 156 | 89 | 79 | 20 | 35 | 117 | 0 | 0 | 0 | 0 | 6 | 3 | 3 | 3.99 |
| SP | Morton, C.Morton, Charlie $$ >> | 30 | 2009 | R | 88 | 21 | 21 | 11 | 7 | 3.56 | .300 | 1.26 | 8.3 | 3.1 | 6.7 | 144.0 | 133 | 61 | 57 | 12 | 49 | 107 | 2 | 0 | 0 | 1 | 13 | 3 | 2 | 3.68 |
| SP | Minor, M.Minor, Mike # $$ >> | 26 | 2013 | L | 85 | 20 | 20 | 7 | 10 | 4.50 | .311 | 1.34 | 8.8 | 3.2 | 5.3 | 128.0 | 125 | 71 | 64 | 18 | 46 | 76 | 1 | 0 | 0 | 0 | 12 | 2 | 5 | 4.77 |
| SP | Anderson, B.Anderson, Brett # $$ >> | 26 | 2009 | L | 76 | 19 | 19 | 6 | 8 | 4.65 | .305 | 1.28 | 8.5 | 3.0 | 8.1 | 120.0 | 113 | 68 | 62 | 22 | 40 | 108 | 1 | 0 | 0 | 0 | 9 | 5 | 0 | 4.71 |
| SP | Davis, W.Davis, Wade $$ >> | 25 | 2010 | R | 65 | 15 | 14 | 1 | 8 | 5.70 | .352 | 1.61 | 10.5 | 4.0 | 6.3 | 79.0 | 92 | 60 | 50 | 19 | 35 | 55 | 1 | 0 | 0 | 0 | 7 | 2 | 0 | 6.14 |
| CL | O'Day, D.O'Day, Darren † $$ >> | 32 | 2009 | R | 93 | 42 | 0 | 3 | 2 | 2.12 | .263 | 1.07 | 5.7 | 4.1 | 7.0 | 46.2 | 29 | 14 | 11 | 1 | 21 | 36 | 0 | 24 | 2 | 0 | 0 | 0 | 0 | 3.09 |
| RP | Villarreal, B.Villarreal, Brayan $$ >> | 27 | 2012 | R | 82 | 53 | 0 | 6 | 4 | 4.83 | .321 | 1.41 | 7.3 | 5.3 | 9.8 | 69.0 | 56 | 41 | 37 | 9 | 41 | 75 | 0 | 2 | 5 | 0 | 0 | 1 | 13 | 4.35 |
| RP | Tolleson, S.Tolleson, Shawn + >> | 26 | 2014 | R | 61 | 41 | 0 | 3 | 0 | 3.86 | .308 | 1.33 | 8.1 | 3.9 | 8.1 | 42.0 | 38 | 19 | 18 | 6 | 18 | 38 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 4.33 |
| RP | Papelbon, J.Papelbon, Jonathan $ >> | 33 | 2006 | R | 41 | 32 | 0 | 0 | 1 | 3.32 | .292 | 1.24 | 8.1 | 3.1 | 7.3 | 38.0 | 34 | 16 | 14 | 4 | 13 | 31 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.76 |
| RP | Mendez, R.Mendez, Roman + >> | 23 | 2014 | R | 28 | 27 | 0 | 1 | 1 | 11.22 | .458 | 2.53 | 15.1 | 8.3 | 8.6 | 25.2 | 42 | 32 | 32 | 7 | 23 | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.48 |
| SP | Gausman, K.Gausman, Kevin + >> | 23 | 2014 | R | 39 | 2 | 0 | 0 | 0 | 23.63 | .500 | 3.00 | 22.5 | 13.5 | 0.0 | 2.2 | 5 | 7 | 7 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 20.50 |