| SP | Peavy, J.Peavy, Jake # $$ >> | 34 | 2002 | R | 100 | 33 | 33 | 16 | 10 | 4.37 | .284 | 1.17 | 8.2 | 2.4 | 7.2 | 222.1 | 202 | 110 | 108 | 41 | 59 | 177 | 3 | 0 | 0 | 0 | 18 | 3 | 5 | 4.64 |
| SP | Scherzer, M.Scherzer, Max $$ >> | 31 | 2008 | R | 99 | 32 | 32 | 13 | 12 | 4.42 | .296 | 1.25 | 8.4 | 2.9 | 7.7 | 213.2 | 199 | 107 | 105 | 32 | 68 | 183 | 6 | 0 | 0 | 1 | 17 | 3 | 3 | 4.23 |
| SP | Brazelton, D.Brazelton, Dewon $$ >> | 32 | 2003 | R | 92 | 30 | 30 | 14 | 9 | 4.44 | .311 | 1.34 | 9.7 | 2.4 | 6.3 | 210.2 | 226 | 108 | 104 | 26 | 56 | 148 | 6 | 0 | 0 | 0 | 15 | 3 | 3 | 4.04 |
| SP | Misch, P.Misch, Patrick $$ >> | 29 | 2008 | L | 90 | 29 | 29 | 13 | 7 | 3.66 | .272 | 1.11 | 7.8 | 2.2 | 6.6 | 204.1 | 177 | 85 | 83 | 25 | 49 | 150 | 8 | 0 | 0 | 1 | 18 | 3 | 2 | 3.89 |
| SP | Vargas, J.Vargas, Jason $$ >> | 32 | 2005 | L | 71 | 24 | 24 | 13 | 9 | 4.19 | .309 | 1.32 | 9.2 | 2.8 | 7.0 | 169.2 | 172 | 85 | 79 | 19 | 52 | 132 | 5 | 0 | 0 | 1 | 12 | 4 | 0 | 3.89 |
| RP | Salas, F.Salas, Fernando $$ >> | 30 | 2011 | R | 99 | 81 | 0 | 5 | 4 | 4.09 | .283 | 1.16 | 7.0 | 3.5 | 8.6 | 83.2 | 65 | 39 | 38 | 10 | 32 | 79 | 0 | 8 | 7 | 0 | 0 | 2 | 2 | 3.89 |
| RP | Norberto, J.Norberto, Jordan $$ >> | 28 | 2012 | L | 98 | 80 | 0 | 1 | 0 | 1.55 | .259 | 1.03 | 5.9 | 3.5 | 7.4 | 52.1 | 34 | 9 | 9 | 1 | 20 | 43 | 0 | 8 | 1 | 0 | 0 | 1 | 3 | 2.81 |
| RP | Cameron, K.Cameron, Kevin # $$ >> | 31 | 2007 | R | 88 | 51 | 0 | 11 | 4 | 4.41 | .301 | 1.26 | 8.1 | 3.3 | 8.3 | 63.1 | 57 | 32 | 31 | 9 | 23 | 58 | 0 | 9 | 7 | 0 | 0 | 2 | 1 | 4.21 |
| RP | Johnson, J.Johnson, Jim $$ >> | 32 | 2008 | R | 84 | 18 | 0 | 2 | 1 | 1.64 | .275 | 1.09 | 4.9 | 4.9 | 6.5 | 22.0 | 12 | 4 | 4 | 0 | 12 | 16 | 0 | 4 | 0 | 0 | 0 | 1 | 1 | 3.32 |
| RP | Aardsma, D.Aardsma, David >> | 34 | 2006 | R | 49 | 19 | 0 | 2 | 0 | 5.96 | .370 | 1.76 | 13.1 | 3.3 | 7.4 | 22.2 | 32 | 15 | 15 | 6 | 8 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.00 |
| SP | Riley, M.Riley, Matt # $$ >> | 33 | 2004 | L | 60 | 20 | 0 | 2 | 0 | 5.31 | .322 | 1.41 | 8.8 | 3.9 | 6.8 | 78.0 | 76 | 47 | 46 | 14 | 34 | 59 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.17 |