| SP | Kershaw, C.Kershaw, Clayton # + $$ >> | 34 | 2014 | L | 100 | 15 | 15 | 8 | 7 | 3.28 | .267 | 1.05 | 7.6 | 1.9 | 8.9 | 118.0 | 99 | 44 | 43 | 15 | 25 | 117 | 6 | 0 | 0 | 0 | 10 | 5 | 3 | 3.43 |
| SP | Arrieta, J.Arrieta, Jake + $$ >> | 36 | 2015 | R | 96 | 15 | 15 | 9 | 5 | 3.52 | .268 | 1.07 | 7.5 | 2.1 | 7.2 | 110.0 | 92 | 43 | 43 | 16 | 26 | 88 | 5 | 0 | 0 | 3 | 8 | 3 | 1 | 4.08 |
| SP | Severino, L.Severino, Luis + $ >> | 28 | 2017 | R | 97 | 15 | 15 | 5 | 9 | 3.92 | .269 | 1.07 | 7.9 | 1.8 | 10.3 | 110.1 | 96 | 50 | 48 | 15 | 22 | 126 | 3 | 0 | 0 | 1 | 7 | 4 | 1 | 3.19 |
| SP | Cain, M.Cain, Matt + $$ >> | 38 | 2011 | R | 83 | 14 | 14 | 5 | 4 | 3.59 | .299 | 1.25 | 8.8 | 2.5 | 7.4 | 97.2 | 95 | 43 | 39 | 9 | 27 | 80 | 1 | 0 | 0 | 1 | 7 | 3 | 2 | 3.48 |
| SP | Crochet, G.Crochet, Garrett + >> | 23 | 2025 | L | 70 | 8 | 8 | 4 | 1 | 2.20 | .240 | 0.91 | 5.9 | 2.4 | 10.3 | 61.1 | 40 | 15 | 15 | 9 | 16 | 70 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 3.51 |
| RP | Kelley, S.Kelley, Shawn + $$ >> | 38 | 2016 | R | 87 | 16 | 0 | 1 | 0 | 2.57 | .300 | 1.21 | 7.7 | 3.2 | 8.4 | 14.0 | 12 | 4 | 4 | 2 | 5 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.29 |
| RP | Bautista, F.Bautista, Felix + $$ >> | 27 | 2022 | R | 89 | 23 | 0 | 2 | 2 | 4.30 | .250 | 1.00 | 5.5 | 3.5 | 9.0 | 23.0 | 14 | 12 | 11 | 3 | 9 | 23 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.87 |
| RP | Smith, C.Smith, Carson $$ >> | 32 | 2015 | R | 94 | 18 | 0 | 2 | 2 | 4.50 | .277 | 1.05 | 6.8 | 2.7 | 13.5 | 20.0 | 15 | 10 | 10 | 2 | 6 | 30 | 0 | 11 | 4 | 0 | 0 | 2 | 2 | 2.50 |
| RP | Gregerson, L.Gregerson, Luke + $ >> | 38 | 2010 | R | 79 | 7 | 0 | 0 | 0 | 2.70 | .375 | 1.80 | 18.0 | 0.0 | 9.0 | 3.1 | 6 | 1 | 1 | 0 | 0 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| RP | Walden, J.Walden, Jordan >> | 34 | 2011 | R | 80 | 6 | 0 | 0 | 0 | 4.76 | .292 | 1.24 | 10.8 | 1.8 | 12.6 | 5.2 | 6 | 3 | 3 | 1 | 1 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.40 |
| RP | Bailey, A.Bailey, Andrew $ >> | 38 | 2009 | R | 82 | 5 | 0 | 0 | 0 | 9.64 | .364 | 1.50 | 13.5 | 2.3 | 15.8 | 4.2 | 6 | 5 | 5 | 3 | 1 | 7 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 10.75 |
| RP | Zumaya, J.Zumaya, Joel >> | 38 | 2006 | R | 81 | 8 | 0 | 0 | 0 | 8.10 | .310 | 1.35 | 9.0 | 4.5 | 6.0 | 6.2 | 6 | 6 | 6 | 1 | 3 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.33 |