| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 34 | 34 | 10 | 16 | 5.23 | .326 | 1.44 | 8.8 | 4.2 | 9.5 | 196.0 | 191 | 124 | 114 | 35 | 91 | 206 | 0 | 0 | 0 | 0 | 18 | 3 | 7 | 4.66 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 73 | 31 | 31 | 9 | 18 | 5.53 | .323 | 1.41 | 9.7 | 3.0 | 7.4 | 198.2 | 213 | 123 | 122 | 22 | 67 | 162 | 5 | 0 | 0 | 0 | 10 | 5 | 2 | 3.90 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 69 | 0 | 1 | 5 | 5.05 | .301 | 1.27 | 7.5 | 4.0 | 10.3 | 76.2 | 63 | 43 | 43 | 14 | 34 | 87 | 0 | 1 | 6 | 0 | 0 | 2 | 0 | 4.53 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 67 | 0 | 5 | 8 | 3.54 | .330 | 1.47 | 7.8 | 5.5 | 9.7 | 73.2 | 63 | 30 | 29 | 9 | 45 | 79 | 0 | 32 | 3 | 0 | 0 | 1 | 2 | 4.33 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 66 | 0 | 2 | 4 | 5.48 | .363 | 1.69 | 10.5 | 4.8 | 8.5 | 67.1 | 78 | 41 | 41 | 12 | 36 | 63 | 0 | 3 | 2 | 0 | 0 | 1 | 2 | 5.10 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 66 | 53 | 0 | 3 | 0 | 3.46 | .295 | 1.24 | 7.0 | 4.3 | 6.9 | 67.2 | 52 | 28 | 26 | 7 | 32 | 51 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 4.31 |