| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 91 | 15 | 15 | 5 | 6 | 4.36 | .295 | 1.25 | 8.7 | 2.5 | 9.5 | 99.0 | 96 | 48 | 48 | 15 | 28 | 104 | 1 | 0 | 0 | 1 | 8 | 0 | 3 | 3.72 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 90 | 15 | 15 | 7 | 6 | 4.25 | .298 | 1.25 | 9.6 | 1.7 | 6.2 | 97.1 | 104 | 47 | 46 | 16 | 18 | 67 | 2 | 0 | 0 | 0 | 9 | 2 | 1 | 4.38 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 14 | 14 | 4 | 8 | 6.50 | .359 | 1.64 | 9.8 | 5.0 | 9.0 | 72.0 | 78 | 56 | 52 | 17 | 40 | 72 | 0 | 0 | 0 | 0 | 4 | 3 | 4 | 5.86 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 84 | 15 | 14 | 4 | 3 | 5.54 | .345 | 1.53 | 9.8 | 4.1 | 8.5 | 79.2 | 86 | 52 | 49 | 12 | 36 | 75 | 0 | 0 | 0 | 0 | 7 | 4 | 3 | 4.59 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 93 | 37 | 0 | 6 | 1 | 3.02 | .251 | 1.01 | 5.7 | 3.5 | 8.8 | 44.2 | 28 | 15 | 15 | 8 | 17 | 43 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 4.57 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 76 | 21 | 0 | 2 | 0 | 5.59 | .326 | 1.34 | 8.1 | 4.3 | 8.1 | 19.1 | 17 | 12 | 12 | 4 | 9 | 17 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.68 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 73 | 16 | 0 | 0 | 1 | 8.56 | .369 | 1.76 | 9.7 | 6.9 | 11.8 | 13.2 | 14 | 13 | 13 | 4 | 10 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.69 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 70 | 21 | 0 | 2 | 0 | 2.88 | .257 | 1.04 | 6.1 | 3.2 | 13.7 | 25.0 | 17 | 10 | 8 | 1 | 9 | 38 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.56 |