| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 37 | 37 | 17 | 11 | 3.26 | .265 | 1.07 | 7.2 | 2.4 | 8.7 | 276.0 | 222 | 110 | 100 | 35 | 73 | 267 | 10 | 0 | 0 | 2 | 26 | 3 | 9 | 3.54 |
| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 95 | 34 | 34 | 18 | 14 | 2.85 | .258 | 1.03 | 7.2 | 2.1 | 7.1 | 259.1 | 208 | 91 | 82 | 29 | 59 | 203 | 12 | 0 | 0 | 2 | 25 | 3 | 5 | 3.61 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 47 | 25 | 25 | 6 | 12 | 5.17 | .335 | 1.51 | 10.1 | 3.5 | 5.7 | 151.1 | 170 | 94 | 87 | 26 | 59 | 95 | 0 | 0 | 0 | 0 | 10 | 0 | 2 | 5.15 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 97 | 63 | 0 | 2 | 7 | 2.19 | .245 | 0.97 | 5.6 | 3.2 | 10.7 | 74.0 | 46 | 19 | 18 | 8 | 26 | 88 | 0 | 40 | 6 | 0 | 0 | 0 | 0 | 3.08 |
| SU | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 98 | 60 | 0 | 1 | 1 | 1.53 | .224 | 0.85 | 4.6 | 3.1 | 11.3 | 59.0 | 30 | 11 | 10 | 4 | 20 | 74 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 2.44 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 99 | 65 | 0 | 5 | 1 | 3.24 | .229 | 0.87 | 5.6 | 2.3 | 9.0 | 58.1 | 36 | 22 | 21 | 12 | 15 | 58 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.52 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 46 | 0 | 3 | 2 | 3.20 | .290 | 1.22 | 7.6 | 3.6 | 10.8 | 25.1 | 21 | 9 | 9 | 3 | 10 | 30 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 3.36 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 34 | 0 | 3 | 1 | 1.69 | .238 | 0.94 | 6.9 | 1.7 | 10.4 | 26.2 | 20 | 5 | 5 | 1 | 5 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.77 |
| SP | Jenkins, F.Jenkins, Fergie >> | 29 | 1971 | R | 35 | 9 | 2 | 1 | 1 | 5.08 | .342 | 1.56 | 11.3 | 2.9 | 6.5 | 44.1 | 55 | 31 | 25 | 9 | 14 | 32 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.16 |