| SP | Ramirez, R.Ramirez, Ramon † >> | 31 | 2008 | R | 99 | 36 | 36 | 16 | 14 | 4.04 | .337 | 1.49 | 9.2 | 4.3 | 7.3 | 220.2 | 224 | 111 | 99 | 12 | 104 | 179 | 1 | 0 | 0 | 0 | 18 | 8 | 0 | 3.61 |
| SP | Albers, A.Albers, Andrew >> | 32 | 2013 | L | 69 | 35 | 35 | 12 | 11 | 5.54 | .357 | 1.63 | 12.7 | 1.9 | 6.2 | 224.1 | 317 | 156 | 138 | 24 | 48 | 154 | 2 | 0 | 0 | 0 | 16 | 9 | 0 | 3.78 |
| SP | Williams, R.Williams, Rick >> | 32 | 1979 | R | 60 | 35 | 35 | 1 | 14 | 6.83 | .399 | 1.95 | 14.0 | 3.6 | 5.2 | 118.2 | 184 | 98 | 90 | 14 | 47 | 68 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 4.71 |
| SP | Madden, M.Madden, Mike >> | 29 | 1983 | L | 74 | 32 | 32 | 2 | 8 | 5.09 | .360 | 1.66 | 10.2 | 4.8 | 5.7 | 106.0 | 120 | 68 | 60 | 9 | 56 | 67 | 0 | 0 | 0 | 0 | 0 | 3 | 4 | 4.51 |
| SP | Pearce, F.Pearce, Frank >> | 33 | 1933 | R | 60 | 30 | 29 | 1 | 6 | 5.91 | .354 | 1.63 | 10.6 | 4.2 | 5.2 | 91.1 | 107 | 67 | 60 | 12 | 42 | 53 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.97 |
| RP | Cather, M.Cather, Mike † >> | 30 | 1997 | R | 93 | 94 | 0 | 18 | 2 | 4.11 | .297 | 1.24 | 7.0 | 4.2 | 7.9 | 124.2 | 96 | 64 | 57 | 7 | 58 | 109 | 0 | 0 | 2 | 0 | 0 | 4 | 0 | 3.48 |
| RP | Leroux, C.Leroux, Chris >> | 28 | 2011 | R | 55 | 81 | 0 | 9 | 3 | 3.35 | .299 | 1.23 | 8.5 | 2.6 | 9.7 | 99.1 | 93 | 40 | 37 | 4 | 29 | 107 | 0 | 7 | 3 | 0 | 0 | 5 | 3 | 2.39 |
| RP | Bibens-Dirkx, A.Bibens-Dirkx, Austin >> | 37 | 2017 | R | 36 | 79 | 0 | 5 | 6 | 4.50 | .338 | 1.49 | 10.5 | 2.9 | 6.5 | 128.0 | 150 | 70 | 64 | 14 | 41 | 92 | 0 | 13 | 4 | 0 | 0 | 5 | 4 | 4.06 |
| SP | Covington, T.Covington, Tex >> | 30 | 1912 | R | 47 | 6 | 1 | 1 | 0 | 2.30 | .266 | 1.09 | 8.4 | 1.8 | 8.4 | 15.2 | 14 | 4 | 4 | 0 | 3 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.73 |
| RP | Thompson, A.Thompson, Aaron >> | 28 | 2015 | L | 45 | 112 | 0 | 4 | 2 | 3.52 | .319 | 1.36 | 9.3 | 2.9 | 6.6 | 92.0 | 95 | 39 | 36 | 6 | 30 | 67 | 0 | 8 | 2 | 0 | 0 | 4 | 4 | 3.50 |