| SP | Buehrle, M.Buehrle, Mark # $$ >> | 29 | 2001 | L | 89 | 24 | 24 | 13 | 9 | 3.72 | .270 | 1.08 | 8.1 | 1.6 | 6.0 | 188.2 | 169 | 79 | 78 | 27 | 34 | 125 | 14 | 0 | 0 | 1 | 12 | 6 | 2 | 4.18 |
| SP | Baker, S.Baker, Scott $$ >> | 27 | 2005 | R | 90 | 24 | 24 | 5 | 10 | 4.79 | .317 | 1.39 | 9.4 | 3.2 | 5.2 | 144.2 | 150 | 80 | 77 | 16 | 51 | 83 | 0 | 0 | 0 | 0 | 10 | 0 | 0 | 4.35 |
| SP | Dempster, R.Dempster, Ryan $$ >> | 31 | 2000 | R | 66 | 22 | 22 | 9 | 10 | 3.76 | .278 | 1.12 | 7.4 | 2.7 | 6.6 | 167.1 | 137 | 72 | 70 | 20 | 50 | 122 | 12 | 0 | 0 | 2 | 13 | 6 | 2 | 4.10 |
| SP | Shields, J.Shields, James $$ >> | 27 | 2007 | R | 67 | 21 | 21 | 5 | 10 | 4.20 | .288 | 1.20 | 8.5 | 2.3 | 5.4 | 154.1 | 146 | 80 | 72 | 25 | 39 | 92 | 5 | 0 | 0 | 0 | 12 | 2 | 6 | 4.71 |
| SP | Harang, A.Harang, Aaron >> | 30 | 2002 | R | 73 | 3 | 3 | 1 | 1 | 5.06 | .360 | 1.63 | 9.0 | 5.6 | 7.9 | 16.0 | 16 | 9 | 9 | 1 | 10 | 14 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.13 |
| RP | Colome, J.Colome, Jesus $$ >> | 31 | 2001 | R | 93 | 52 | 0 | 3 | 1 | 2.44 | .268 | 1.09 | 7.4 | 2.5 | 7.0 | 62.2 | 51 | 17 | 17 | 7 | 17 | 48 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 3.79 |
| RP | Jenks, B.Jenks, Bobby $$ >> | 27 | 2007 | R | 89 | 39 | 0 | 4 | 3 | 2.93 | .271 | 1.07 | 7.1 | 2.5 | 4.4 | 43.0 | 34 | 15 | 14 | 2 | 12 | 21 | 0 | 6 | 3 | 0 | 0 | 2 | 2 | 3.60 |
| RP | Orvella, C.Orvella, Chad $$ >> | 28 | 2005 | R | 79 | 16 | 0 | 3 | 1 | 2.89 | .300 | 1.29 | 8.5 | 3.5 | 5.0 | 18.2 | 17 | 6 | 6 | 3 | 7 | 10 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 5.22 |
| RP | Corpas, M.Corpas, Manuel $$ >> | 26 | 2007 | R | 69 | 10 | 0 | 0 | 0 | 2.08 | .250 | 1.00 | 7.6 | 1.4 | 6.2 | 13.0 | 11 | 3 | 3 | 2 | 2 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.08 |
| RP | Cotts, N.Cotts, Neal $$ >> | 28 | 2005 | L | 97 | 46 | 0 | 1 | 3 | 7.88 | .410 | 2.08 | 10.1 | 8.6 | 9.0 | 24.0 | 27 | 22 | 21 | 3 | 23 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 5.50 |
| RP | Yan, E.Yan, Esteban $$ >> | 33 | 1998 | R | 58 | 15 | 0 | 2 | 0 | 1.86 | .275 | 1.14 | 6.6 | 3.8 | 5.2 | 19.1 | 14 | 4 | 4 | 2 | 8 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.47 |
| SP | Froneberger, I.Froneberger, Isiah + $$ >> | 22 | 2026 | L | 57 | 11 | 0 | 0 | 0 | 5.05 | .322 | 1.40 | 11.2 | 1.6 | 6.1 | 46.1 | 57 | 26 | 26 | 9 | 8 | 31 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.78 |