| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 6 | 6 | 2 | 0 | 3.00 | .270 | 1.07 | 7.8 | 1.8 | 10.2 | 45.0 | 39 | 15 | 15 | 8 | 9 | 51 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 3.78 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 89 | 6 | 6 | 2 | 3 | 6.57 | .355 | 1.65 | 11.7 | 3.2 | 9.7 | 37.0 | 48 | 28 | 27 | 5 | 13 | 40 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 3.65 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 83 | 6 | 6 | 2 | 2 | 5.62 | .313 | 1.30 | 8.6 | 3.3 | 8.3 | 41.2 | 39 | 26 | 26 | 3 | 15 | 38 | 2 | 0 | 0 | 0 | 2 | 3 | 0 | 3.41 |
| SP | McClanahan, S.McClanahan, Shane # >> | 25 | 2022 | L | 72 | 5 | 5 | 1 | 2 | 5.18 | .340 | 1.52 | 10.4 | 3.3 | 8.2 | 33.0 | 38 | 19 | 19 | 6 | 12 | 30 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 4.73 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 71 | 4 | 4 | 0 | 3 | 6.04 | .309 | 1.30 | 9.7 | 2.2 | 6.5 | 25.1 | 27 | 18 | 17 | 5 | 6 | 18 | 1 | 0 | 0 | 0 | 2 | 1 | 0 | 5.00 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 74 | 19 | 0 | 1 | 1 | 1.20 | .151 | 0.53 | 3.6 | 1.2 | 11.4 | 15.0 | 6 | 2 | 2 | 2 | 2 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.60 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 72 | 15 | 0 | 2 | 0 | 0.93 | .121 | 0.41 | 1.0 | 3.0 | 9.0 | 9.2 | 1 | 2 | 1 | 0 | 3 | 9 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 71 | 8 | 0 | 2 | 0 | 0.00 | .211 | 0.80 | 3.6 | 3.6 | 3.6 | 5.0 | 2 | 0 | 0 | 0 | 2 | 2 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.40 |
| RP | Quisenberry, D.Quisenberry, Dan >> | 30 | 1983 | R | 24 | 6 | 0 | 1 | 0 | 5.25 | .321 | 1.42 | 10.5 | 2.3 | 5.3 | 12.0 | 14 | 7 | 7 | 3 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.83 |