| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 89 | 31 | 31 | 15 | 8 | 3.49 | .296 | 1.24 | 7.2 | 4.0 | 7.9 | 193.2 | 155 | 81 | 75 | 18 | 85 | 169 | 4 | 0 | 0 | 1 | 19 | 4 | 5 | 3.84 |
| SP | McNally, D.McNally, Dave † # >> | 26 | 1968 | L | 95 | 30 | 30 | 15 | 8 | 3.90 | .284 | 1.16 | 7.8 | 2.7 | 4.7 | 189.1 | 164 | 86 | 82 | 17 | 56 | 98 | 6 | 0 | 0 | 4 | 16 | 5 | 6 | 4.10 |
| SP | Prior, M.Prior, Mark # >> | 23 | 2003 | R | 12 | 28 | 20 | 12 | 6 | 3.93 | .308 | 1.31 | 8.9 | 2.9 | 7.7 | 162.2 | 160 | 76 | 71 | 21 | 53 | 139 | 2 | 0 | 0 | 1 | 12 | 4 | 5 | 4.02 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 54 | 28 | 28 | 7 | 10 | 4.98 | .326 | 1.42 | 9.8 | 3.0 | 8.3 | 166.1 | 180 | 104 | 92 | 18 | 56 | 153 | 1 | 0 | 0 | 0 | 12 | 5 | 2 | 3.67 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 57 | 20 | 19 | 6 | 11 | 5.28 | .310 | 1.34 | 9.3 | 2.7 | 4.4 | 104.0 | 108 | 66 | 61 | 12 | 31 | 51 | 7 | 0 | 0 | 2 | 8 | 1 | 3 | 4.44 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 65 | 68 | 0 | 4 | 2 | 1.74 | .261 | 1.03 | 6.3 | 3.0 | 7.8 | 88.0 | 62 | 19 | 17 | 7 | 29 | 76 | 0 | 5 | 4 | 0 | 0 | 2 | 3 | 3.36 |
| RP | Kimbrel, C.Kimbrel, Craig # >> | 24 | 2012 | R | 100 | 49 | 0 | 3 | 7 | 3.19 | .262 | 1.05 | 6.0 | 3.5 | 9.4 | 67.2 | 45 | 30 | 24 | 3 | 26 | 70 | 0 | 4 | 3 | 0 | 0 | 1 | 4 | 2.70 |
| RP | Eckersley, D.Eckersley, Dennis # >> | 36 | 1990 | R | 89 | 47 | 0 | 1 | 2 | 4.81 | .336 | 1.46 | 9.9 | 3.4 | 6.9 | 48.2 | 53 | 28 | 26 | 7 | 18 | 37 | 0 | 5 | 3 | 0 | 0 | 3 | 0 | 4.67 |
| RP | Pressly, R.Pressly, Ryan >> | 30 | 2019 | R | 50 | 6 | 0 | 0 | 1 | 5.40 | .355 | 1.50 | 10.5 | 4.5 | 10.5 | 6.2 | 7 | 4 | 4 | 1 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.83 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 58 | 19 | 0 | 0 | 2 | 7.11 | .352 | 1.58 | 8.5 | 5.7 | 7.6 | 19.0 | 18 | 16 | 15 | 4 | 12 | 16 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 6.11 |