| SP | Samardzija, J.Samardzija, Jeff | Cubs | R | 181.0 | 30 | 29 | 22 | 4 | 2.05 | .243 | 0.96 | 6.4 | 2.2 | 8.8 | 189.0 | 134 | 48 | 43 | 14 | 47 | 185 | 1 | 0 | 0 | 1 | 21 | 1 | 2 | 2.77 |
| SP | Scherzer, M.Scherzer, Max † | Diamondbacks | R | 177.0 | 36 | 36 | 21 | 7 | 2.81 | .259 | 1.02 | 6.8 | 2.4 | 10.9 | 246.2 | 185 | 78 | 77 | 23 | 66 | 297 | 2 | 0 | 0 | 1 | 29 | 7 | 0 | 2.69 |
| SP | Giolito, L.Giolito, Lucas † | Braves | R | 170.0 | 37 | 37 | 19 | 6 | 2.66 | .279 | 1.14 | 6.6 | 3.7 | 11.1 | 240.2 | 176 | 75 | 71 | 32 | 98 | 297 | 1 | 0 | 0 | 0 | 25 | 5 | 3 | 3.55 |
| SP | Kershaw, C.Kershaw, Clayton # | Dodgers | L | 135.0 | 41 | 41 | 18 | 20 | 3.14 | .265 | 1.06 | 7.0 | 2.5 | 9.3 | 283.1 | 221 | 103 | 99 | 30 | 78 | 293 | 2 | 0 | 0 | 1 | 26 | 8 | 6 | 3.22 |
| SP | Flaherty, J.Flaherty, Jack | Cardinals | R | 133.0 | 38 | 38 | 18 | 9 | 3.55 | .298 | 1.22 | 7.9 | 3.1 | 10.8 | 238.1 | 210 | 97 | 94 | 21 | 81 | 286 | 0 | 0 | 0 | 0 | 22 | 12 | 6 | 2.92 |
| SP | deGrom, J.deGrom, Jacob † | Mets | R | 130.0 | 37 | 37 | 19 | 11 | 3.79 | .292 | 1.21 | 8.7 | 2.3 | 11.1 | 244.2 | 235 | 115 | 103 | 30 | 62 | 301 | 0 | 0 | 0 | 0 | 25 | 6 | 1 | 2.97 |