| SP | Parry, B.Parry, Britain † $$ | Reds | R | 230.0 | 35 | 35 | 23 | 9 | 2.34 | .222 | 0.84 | 6.5 | 1.1 | 7.0 | 299.2 | 215 | 86 | 78 | 29 | 38 | 234 | 21 | 0 | 0 | 5 | 27 | 3 | 1 | 3.11 |
| SP | Maddux, G.Maddux, Greg † # $$ | Diamondbacks | R | 183.0 | 34 | 34 | 21 | 7 | 3.45 | .244 | 0.95 | 7.1 | 1.4 | 7.7 | 287.1 | 227 | 114 | 110 | 39 | 45 | 246 | 21 | 0 | 0 | 2 | 20 | 6 | 5 | 3.59 |
| SP | Harden, R.Harden, Rich $$ | Padres | R | 161.0 | 34 | 34 | 21 | 7 | 3.09 | .285 | 1.17 | 6.7 | 3.9 | 9.0 | 233.0 | 173 | 86 | 80 | 16 | 100 | 232 | 2 | 0 | 0 | 0 | 24 | 6 | 4 | 3.27 |
| SP | McHale, C.McHale, Chaz $$ | Diamondbacks | R | 160.0 | 35 | 35 | 21 | 10 | 3.64 | .271 | 1.08 | 7.8 | 1.9 | 9.4 | 271.2 | 235 | 113 | 110 | 39 | 58 | 283 | 9 | 0 | 0 | 3 | 21 | 10 | 3 | 3.54 |
| SP | Scott, M.Scott, Mike † $$ | Mets | R | 146.0 | 36 | 36 | 17 | 9 | 3.39 | .273 | 1.10 | 7.3 | 2.6 | 8.8 | 252.0 | 205 | 99 | 95 | 30 | 72 | 247 | 13 | 0 | 0 | 1 | 22 | 7 | 5 | 3.53 |
| SP | Skenes, P.Skenes, Paul † $$ | Mets | R | 141.0 | 35 | 35 | 18 | 10 | 3.22 | .267 | 1.07 | 7.7 | 1.9 | 9.3 | 237.1 | 203 | 89 | 85 | 20 | 50 | 246 | 3 | 0 | 0 | 2 | 26 | 6 | 3 | 2.73 |
| SP | Addison, A.Addison, Andy $$ | Diamondbacks | R | 138.0 | 33 | 33 | 16 | 13 | 3.29 | .266 | 1.07 | 6.9 | 2.8 | 6.7 | 270.2 | 207 | 101 | 99 | 36 | 83 | 201 | 16 | 0 | 0 | 1 | 19 | 5 | 4 | 4.22 |
| SP | Lavelle, R.Lavelle, Rocky # $$ | Cardinals | R | 136.0 | 34 | 34 | 17 | 12 | 3.33 | .282 | 1.16 | 7.4 | 3.0 | 6.9 | 259.1 | 214 | 105 | 96 | 26 | 86 | 200 | 11 | 0 | 0 | 1 | 21 | 6 | 11 | 3.83 |