| SP | Rodriguez, E.Rodriguez, Eduardo † | Reds | L | 126.0 | 22 | 22 | 14 | 5 | 2.73 | .213 | 0.76 | 5.7 | 1.2 | 7.5 | 184.1 | 117 | 57 | 56 | 23 | 24 | 154 | 8 | 0 | 0 | 0 | 16 | 9 | 2 | 3.49 |
| CL | Hader, J.Hader, Josh † $$ | Braves | L | 107.5 | 43 | 0 | 4 | 3 | 1.74 | .225 | 0.85 | 4.9 | 2.8 | 11.5 | 51.2 | 28 | 10 | 10 | 3 | 16 | 65 | 0 | 29 | 2 | 0 | 0 | 1 | 0 | 2.22 |
| SP | Flaherty, J.Flaherty, Jack † # $$ | Pirates | R | 105.0 | 23 | 23 | 11 | 5 | 2.68 | .223 | 0.85 | 5.9 | 1.8 | 9.6 | 151.1 | 99 | 46 | 45 | 15 | 30 | 161 | 6 | 0 | 0 | 3 | 14 | 1 | 5 | 2.77 |
| SP | Gallen, Z.Gallen, Zac † $$ | Braves | R | 102.0 | 22 | 22 | 10 | 6 | 2.31 | .225 | 0.84 | 5.6 | 2.0 | 8.3 | 156.0 | 97 | 46 | 40 | 13 | 34 | 143 | 4 | 0 | 0 | 3 | 18 | 5 | 2 | 3.00 |
| CL | Chapman, A.Chapman, Aroldis † $$ | Giants | L | 87.0 | 37 | 0 | 3 | 3 | 2.06 | .281 | 1.17 | 6.4 | 4.1 | 11.1 | 35.0 | 25 | 9 | 8 | 4 | 16 | 43 | 0 | 26 | 1 | 0 | 0 | 0 | 0 | 3.40 |
| SP | Javier, C.Javier, Cristian † $$ | Cubs | R | 86.0 | 23 | 23 | 11 | 6 | 3.19 | .279 | 1.11 | 7.6 | 2.4 | 10.6 | 144.0 | 122 | 53 | 51 | 18 | 38 | 169 | 0 | 0 | 0 | 0 | 17 | 7 | 3 | 3.22 |
| CL | Alvarado, J.Alvarado, Jose † $$ | Cubs | L | 84.5 | 49 | 0 | 6 | 4 | 2.76 | .249 | 0.97 | 6.2 | 2.5 | 9.0 | 78.1 | 54 | 24 | 24 | 3 | 22 | 78 | 0 | 17 | 5 | 0 | 0 | 2 | 1 | 2.42 |
| SP | Soroka, M.Soroka, Mike $$ | Braves | R | 80.0 | 22 | 22 | 10 | 7 | 3.36 | .253 | 1.00 | 7.5 | 1.6 | 6.9 | 147.1 | 122 | 63 | 55 | 20 | 26 | 112 | 6 | 0 | 0 | 3 | 13 | 2 | 1 | 3.82 |
| SP | Giolito, L.Giolito, Lucas # $$ | Giants | R | 74.0 | 23 | 23 | 12 | 9 | 4.06 | .252 | 0.97 | 6.3 | 2.5 | 9.9 | 150.2 | 105 | 70 | 68 | 27 | 41 | 165 | 4 | 0 | 0 | 0 | 15 | 6 | 2 | 4.08 |
| RP | Edwards, C.Edwards, Carl † $$ | Cardinals | R | 71.0 | 47 | 0 | 6 | 3 | 2.00 | .222 | 0.81 | 3.9 | 3.5 | 11.3 | 67.2 | 29 | 17 | 15 | 4 | 26 | 84 | 0 | 8 | 2 | 0 | 0 | 3 | 2 | 2.57 |