| SP | Cole, G.Cole, Gerrit † + $$ | Red Sox | R | 198.0 | 40 | 40 | 23 | 12 | 3.11 | .238 | 0.91 | 6.6 | 1.6 | 10.4 | 304.1 | 224 | 105 | 105 | 55 | 53 | 351 | 13 | 0 | 0 | 2 | 28 | 8 | 3 | 3.64 |
| SP | Peralta, F.Peralta, Freddy † $$ | Mariners | R | 189.0 | 39 | 39 | 22 | 4 | 2.80 | .262 | 1.04 | 6.5 | 2.8 | 10.6 | 254.0 | 183 | 83 | 79 | 28 | 80 | 299 | 1 | 0 | 0 | 0 | 26 | 8 | 5 | 3.12 |
| SP | Teheran, J.Teheran, Julio † + $$ | Orioles | R | 179.0 | 37 | 37 | 20 | 12 | 3.03 | .258 | 1.01 | 7.4 | 1.7 | 8.6 | 285.1 | 234 | 103 | 96 | 29 | 55 | 271 | 13 | 0 | 0 | 6 | 24 | 9 | 4 | 3.09 |
| CL | Knebel, C.Knebel, Corey † + $$ | Twins | R | 160.5 | 80 | 0 | 8 | 13 | 3.10 | .279 | 1.11 | 7.5 | 2.5 | 10.8 | 78.1 | 65 | 27 | 27 | 7 | 22 | 94 | 0 | 51 | 4 | 0 | 0 | 4 | 1 | 2.76 |
| SP | Cortes Jr., N.Cortes Jr., Nestor # + $$ | Angels | L | 160.0 | 39 | 39 | 18 | 14 | 2.98 | .232 | 0.88 | 6.4 | 1.6 | 11.4 | 281.0 | 199 | 93 | 93 | 40 | 49 | 357 | 4 | 0 | 0 | 2 | 26 | 6 | 4 | 2.90 |
| SP | Wacha, M.Wacha, Michael † $$ | Angels | R | 151.0 | 37 | 37 | 17 | 4 | 2.72 | .254 | 0.98 | 6.9 | 1.9 | 8.1 | 228.2 | 175 | 75 | 69 | 17 | 48 | 205 | 0 | 0 | 0 | 0 | 23 | 10 | 3 | 2.93 |
| SP | Bumgarner, M.Bumgarner, Madison + $$ | Blue Jays | L | 147.0 | 37 | 37 | 13 | 13 | 2.71 | .238 | 0.89 | 6.9 | 1.2 | 10.2 | 258.2 | 198 | 98 | 78 | 38 | 33 | 293 | 14 | 0 | 0 | 5 | 25 | 11 | 2 | 3.16 |
| SP | Cingrani, T.Cingrani, Tony $$ | Red Sox | L | 144.0 | 39 | 39 | 15 | 9 | 2.87 | .232 | 0.88 | 5.6 | 2.3 | 10.5 | 251.0 | 156 | 88 | 80 | 37 | 64 | 294 | 2 | 0 | 0 | 2 | 29 | 7 | 2 | 3.42 |
| SP | Rodon, C.Rodon, Carlos + $$ | Twins | L | 143.0 | 36 | 36 | 18 | 9 | 3.26 | .268 | 1.07 | 8.1 | 1.5 | 10.7 | 240.0 | 215 | 93 | 87 | 30 | 41 | 286 | 1 | 0 | 0 | 1 | 23 | 7 | 8 | 2.84 |
| CL | Bautista, F.Bautista, Felix † | White Sox | R | 137.5 | 59 | 0 | 4 | 4 | 2.57 | .256 | 0.97 | 5.7 | 3.0 | 11.9 | 63.0 | 40 | 18 | 18 | 2 | 21 | 83 | 0 | 43 | 5 | 0 | 0 | 4 | 0 | 1.97 |