| SP | Martinez, P.Martinez, Pedro † | Warriors | R | 170.0 | 37 | 37 | 19 | 12 | 3.17 | .275 | 1.10 | 7.7 | 2.3 | 10.2 | 287.0 | 244 | 111 | 101 | 29 | 72 | 324 | 11 | 0 | 0 | 3 | 23 | 10 | 4 | 2.91 |
| SP | Greinke, Z.Greinke, Zack # | Warriors | R | 136.0 | 34 | 34 | 21 | 8 | 4.13 | .297 | 1.23 | 8.8 | 2.4 | 9.2 | 237.2 | 231 | 111 | 109 | 28 | 62 | 242 | 5 | 0 | 0 | 0 | 20 | 8 | 4 | 3.38 |
| SP | Perez, O.Perez, Oliver † $$ | Suns | L | 132.0 | 32 | 32 | 17 | 1 | 3.20 | .292 | 1.21 | 6.9 | 4.1 | 8.3 | 180.0 | 137 | 70 | 64 | 20 | 81 | 166 | 0 | 0 | 0 | 0 | 18 | 5 | 4 | 4.03 |
| CL | Rivera, M.Rivera, Mariano † $ | 2000 | R | 128.5 | 71 | 0 | 3 | 5 | 3.54 | .264 | 1.08 | 7.5 | 2.3 | 9.4 | 68.2 | 57 | 29 | 27 | 9 | 17 | 71 | 0 | 47 | 9 | 0 | 0 | 0 | 1 | 3.38 |
| SP | Clemens, R.Clemens, Roger † | Hornets | R | 124.0 | 36 | 36 | 18 | 8 | 3.76 | .312 | 1.32 | 8.0 | 3.9 | 7.3 | 242.0 | 215 | 110 | 101 | 25 | 105 | 197 | 1 | 0 | 0 | 0 | 22 | 9 | 4 | 4.13 |
| CL | Papelbon, J.Papelbon, Jonathan † $$ | Lady Gagas | R | 119.5 | 72 | 0 | 3 | 6 | 3.04 | .291 | 1.22 | 8.2 | 2.8 | 9.6 | 77.0 | 70 | 27 | 26 | 6 | 24 | 82 | 0 | 39 | 3 | 0 | 0 | 1 | 2 | 2.86 |
| SP | Buehrle, M.Buehrle, Mark † | 2000 | L | 113.0 | 33 | 33 | 17 | 6 | 3.77 | .299 | 1.26 | 8.5 | 2.8 | 6.3 | 214.2 | 203 | 94 | 90 | 34 | 67 | 150 | 0 | 0 | 0 | 0 | 18 | 5 | 2 | 4.67 |
| SP | Halladay, R.Halladay, Roy # $ | 2000 | R | 113.0 | 35 | 35 | 14 | 13 | 3.41 | .282 | 1.14 | 8.1 | 2.1 | 6.4 | 253.1 | 229 | 102 | 96 | 35 | 60 | 179 | 10 | 0 | 0 | 1 | 22 | 9 | 3 | 4.20 |