| CL | Urbina, U.Urbina, Ugueth † $$ | Blue Jays | R | 172.5 | 72 | 0 | 7 | 4 | 1.20 | .226 | 0.86 | 4.5 | 3.3 | 9.1 | 90.1 | 45 | 15 | 12 | 2 | 33 | 91 | 0 | 41 | 2 | 0 | 0 | 1 | 1 | 2.40 |
| SP | LaChapelle, Y.LaChapelle, Yan † $$ | Angels | L | 166.0 | 35 | 35 | 21 | 7 | 3.64 | .300 | 1.26 | 8.1 | 3.3 | 8.4 | 274.1 | 248 | 121 | 111 | 31 | 99 | 255 | 11 | 0 | 0 | 2 | 23 | 5 | 16 | 3.75 |
| SP | McKnight, T.McKnight, Tony $$ | Angels | R | 164.0 | 38 | 38 | 22 | 7 | 3.45 | .282 | 1.13 | 7.3 | 2.8 | 5.6 | 282.0 | 229 | 117 | 108 | 30 | 89 | 175 | 4 | 0 | 0 | 2 | 22 | 14 | 5 | 4.24 |
| SP | Buehrle, M.Buehrle, Mark $$ | White Sox | L | 152.0 | 33 | 33 | 20 | 10 | 3.36 | .282 | 1.17 | 8.1 | 2.4 | 5.7 | 254.2 | 228 | 102 | 95 | 44 | 69 | 162 | 13 | 0 | 0 | 0 | 20 | 3 | 5 | 4.83 |
| CL | Benitez, A.Benitez, Armando † $$ | Orioles | R | 151.5 | 76 | 0 | 4 | 4 | 2.02 | .242 | 0.95 | 5.9 | 2.7 | 7.7 | 80.1 | 52 | 20 | 18 | 8 | 24 | 68 | 0 | 45 | 4 | 0 | 0 | 1 | 0 | 3.54 |
| SP | Perez, O.Perez, Odalis $$ | Twins | L | 149.0 | 38 | 38 | 19 | 13 | 3.28 | .270 | 1.09 | 7.7 | 2.2 | 5.8 | 274.1 | 233 | 109 | 100 | 40 | 66 | 176 | 10 | 0 | 0 | 4 | 24 | 5 | 5 | 4.39 |
| CL | Rodriguez, F.Rodriguez, Francisco † $$ | Angels | R | 147.0 | 63 | 0 | 11 | 6 | 3.24 | .260 | 1.01 | 5.4 | 3.7 | 9.2 | 75.0 | 45 | 27 | 27 | 11 | 31 | 77 | 0 | 36 | 6 | 0 | 0 | 3 | 3 | 4.21 |