| SP | Guzman, P.Guzman, Pat >> | 34 | 2021 | R | 11 | 21 | 9 | 4.24 | .270 | .350 | 1.13 | 8.0 | 2.1 | 8.8 | 199 | 177 | 21 | 47 | 195 | 7 | 0 | 24 | 113 | 14 | A |
| SP | Leftwich, G.Leftwich, George >> | 37 | 2021 | R | 9 | 20 | 7 | 2.97 | .270 | .350 | 1.13 | 8.0 | 2.1 | 7.7 | 194 | 173 | 17 | 46 | 166 | 0 | 0 | 7 | 90 | 18 | A |
| SP | Atwater, F.Atwater, Frank >> | 38 | 2021 | L | 5 | 19 | 9 | 4.13 | .276 | .360 | 1.16 | 8.3 | 2.2 | 5.5 | 164 | 151 | 15 | 40 | 101 | 0 | 0 | 4 | 101 | 12 | A |
| SP | Hall, R.Hall, Ron >> | 38 | 2021 | R | 7 | 18 | 6 | 3.74 | .273 | .360 | 1.15 | 8.4 | 1.9 | 6.4 | 160 | 150 | 15 | 34 | 113 | 0 | 0 | 5 | 109 | 10 | A |
| SP | Mozart, M.Mozart, Manny >> | 39 | 2021 | R | 12 | 17 | 10 | 3.36 | .258 | .340 | 1.06 | 7.3 | 2.3 | 5.8 | 210 | 170 | 15 | 53 | 135 | 6 | 0 | 9 | 120 | 13 | A |
| SP | Hayden, G.Hayden, Grant >> | 36 | 2022 | R | 5 | 16 | 8 | 3.91 | .278 | .360 | 1.17 | 8.6 | 2.0 | 7.3 | 221 | 210 | 22 | 49 | 179 | 0 | 0 | 12 | 111 | 17 | A |
| SP | Bradley, J.Bradley, Jon >> | 39 | 2021 | R | 3 | 15 | 7 | 3.80 | .295 | .380 | 1.28 | 8.9 | 2.6 | 7.2 | 163 | 162 | 11 | 47 | 130 | 4 | 0 | 9 | 115 | 12 | A |
| SP | Manuel, J.Manuel, Jon >> | 39 | 2021 | L | 4 | 15 | 3 | 2.16 | .283 | .370 | 1.20 | 7.9 | 2.9 | 6.2 | 187 | 164 | 11 | 61 | 128 | 1 | 0 | 10 | 107 | 9 | A |
| SP | Whiting, R.Whiting, Rob >> | 37 | 2022 | L | 7 | 14 | 9 | 2.78 | .271 | .360 | 1.14 | 8.3 | 2.0 | 7.2 | 168 | 154 | 16 | 37 | 135 | 1 | 0 | 12 | 118 | 14 | U |
| SP | Fields, T.Fields, Trevor >> | 39 | 2021 | L | 6 | 14 | 6 | 3.49 | .281 | .370 | 1.19 | 7.8 | 2.9 | 6.3 | 191 | 166 | 6 | 62 | 133 | 1 | 0 | 6 | 100 | 17 | A |
| SP | Peach, J.Peach, James >> | 38 | 2021 | R | 11 | 14 | 10 | 3.82 | .274 | .360 | 1.15 | 8.2 | 2.1 | 9.1 | 177 | 162 | 22 | 42 | 178 | 0 | 0 | 8 | 100 | 17 | A |
| SP | Jackson, B.Jackson, Blaine >> | 35 | 2022 | R | 2 | 13 | 5 | 3.26 | .297 | .380 | 1.29 | 9.2 | 2.5 | 7.7 | 176 | 179 | 20 | 48 | 150 | 1 | 0 | 3 | 89 | 14 | U |
| SP | Romero, L.Romero, Luis >> | 39 | 2021 | L | 7 | 12 | 6 | 3.50 | .281 | .370 | 1.19 | 7.9 | 2.8 | 7.1 | 214 | 189 | 20 | 66 | 170 | 1 | 0 | 8 | 103 | 13 | C |
| SP | Hooks, H.Hooks, Hollis >> | 36 | 2021 | R | 9 | 12 | 9 | 4.22 | .263 | .350 | 1.09 | 8.3 | 1.5 | 7.9 | 180 | 166 | 13 | 30 | 157 | 0 | 0 | 13 | 91 | 18 | C |
| SP | Mattson, M.Mattson, Michael >> | 39 | 2021 | R | 2 | 11 | 7 | 4.31 | .308 | .390 | 1.36 | 9.2 | 3.1 | 7.7 | 168 | 172 | 19 | 57 | 144 | 1 | 0 | 1 | 86 | 8 | U |
| SP | Garcia, L.Garcia, Luis >> | 38 | 2021 | R | 1 | 11 | 8 | 3.30 | .296 | .380 | 1.28 | 9.1 | 2.5 | 7.2 | 169 | 170 | 19 | 47 | 136 | 0 | 0 | 9 | 94 | 17 | A |
| SP | Grunhard, E.Grunhard, Elliott >> | 36 | 2022 | R | 13 | 11 | 10 | 3.48 | .266 | .350 | 1.11 | 7.2 | 2.8 | 8.0 | 170 | 136 | 11 | 52 | 151 | 0 | 0 | 11 | 110 | 11 | F |
| SP | Ford, B.Ford, Blake >> | 38 | 2021 | R | 1 | 10 | 10 | 2.95 | .302 | .390 | 1.32 | 9.0 | 2.9 | 7.0 | 170 | 170 | 18 | 55 | 132 | 2 | 0 | 4 | 100 | 13 | C |
| SP | Redding, B.Redding, Bradley >> | 37 | 2022 | R | 4 | 9 | 7 | 4.81 | .282 | .370 | 1.20 | 8.5 | 2.3 | 7.2 | 182 | 171 | 14 | 47 | 146 | 0 | 0 | 11 | 91 | 5 | F |
| SP | Guillen, A.Guillen, Archie >> | 37 | 2022 | L | 3 | 9 | 10 | 4.84 | .283 | .370 | 1.21 | 9.1 | 1.8 | 7.2 | 162 | 163 | 17 | 33 | 130 | 1 | 0 | 4 | 91 | 14 | A |
| SP | Cannizzaro, D.Cannizzaro, Donn >> | 38 | 2021 | R | 6 | 8 | 8 | 5.94 | .276 | .360 | 1.17 | 8.1 | 2.3 | 5.8 | 169 | 153 | 16 | 44 | 108 | 1 | 0 | 14 | 117 | 10 | F |
| SP | McKenzie, T.McKenzie, Treat >> | 38 | 2021 | R | 8 | 8 | 12 | 4.95 | .294 | .380 | 1.27 | 7.3 | 4.1 | 7.7 | 196 | 159 | 31 | 90 | 168 | 0 | 0 | 3 | 86 | 18 | A |
| SP | Rogers, T.Rogers, Trevor >> | 38 | 2021 | L | 4 | 7 | 8 | 2.64 | .293 | .380 | 1.27 | 8.9 | 2.6 | 7.7 | 148 | 146 | 6 | 42 | 127 | 0 | 0 | 4 | 90 | 19 | A |