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| Week | Date/Opp | Result | Pass | Rush | Rec | ||
|---|---|---|---|---|---|---|---|
| 16 | 11/26 Panthers | L 30-19 | Vick, 175 | Brown, 130 | Smith, 86 | ||
| 15 | 11/25 Lions | W 26-20 | Manning, 286 | Brown, 171 | Smith, 82 | ||
| 14 | 11/24 @Vikings | W 30-23 | Culpepper, 293 | Brown, 99 | Smith, 126 | ||
| 13 | 11/23 @Panthers | W 27-24 | Vick, 213 | Brown, 132 | Smith, 63 | ||
| 12 | 11/22 49ers | W 26-17 | Rivers, 142 | Brown, 141 | Smith, 66 | ||
| 11 | 11/21 @Packers | W 48-8 | Schaub, 231 | Brown, 177 | Smith, 81 | ||
| 10 | 11/20 Eagles | W 50-3 | Schaub, 317 | Brown, 181 | Smith, 102 | ||
| 9 | 11/19 Lions | W 30-18 | Manning, 281 | Brown, 87 | Boston, 75 | ||
| 8 | 11/18 @Cowboys | W 22-0 | Schaub, 164 | Brown, 152 | Jackson, 67 | ||
| 7 | 11/17 Vikings | W 22-17 | Schaub, 273 | Culpepper, 92 | Smith, 96 | ||
| 6 | 11/16 Panthers | L 23-21 | Schaub, 214 | James, 96 | Burleson, 85 | ||
| 5 | 11/15 @49ers | L 20-3 | Schaub, 236 | Green, 77 | Brooks, 90 | ||
| 4 | 11/14 Packers | W 27-21 | Brees, 265 | Brown, 144 | Smith, 81 | ||
| 3 | 11/13 @Eagles | W 37-30 | McNabb, 197 | Brown, 147 | Moss, 95 | ||
| 2 | 11/12 @Lions | W 17-14 | Schaub, 205 | Brown, 101 | Smith, 73 | ||
| 1 | 11/11 Cowboys | L 37-28 | Schaub, 250 | Johnson, 104 | Branch, 103 | ||
| See Full Season | |||||||
- Trophy Case
- 2010 Division Champs | roster
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