Playoff Series Breakdown
| First Round Playoff: Braves @ Brewers | ||
| 1 | Brewers 8, Braves 3 | WP: Sotelo LP: Ratchford |
| 2 | Brewers 7, Braves 2 | WP: Sisley LP: Totten |
| Brewers Win Series 2-0 | ||
| First Round Playoff: Padres @ Giants | ||
| 1 | Giants 4, Padres 2 | WP: Seery LP: Jara |
| 2 | Giants 5, Padres 4 | WP: Weyrauch LP: Bari |
| Giants Win Series 2-0 | ||
| First Round Playoff: Mariners @ Guardians | ||
| 1 | Guardians 5, Mariners 0 | WP: Vande Zandschulp LP: Grayson |
| 2 | Guardians 6, Mariners 4 | WP: Barrameda LP: Lafromboise |
| Guardians Win Series 2-0 | ||
| First Round Playoff: Expos @ Angels | ||
| 1 | Angels 6, Expos 5 | WP: Singleton LP: Kergoat |
| 2 | Expos 4, Angels 0 | WP: Baz LP: Anna |
| 3 | Angels 11, Expos 2 | WP: de la Hoz LP: Cara |
| Angels Win Series 2-1 | ||
| Second Round Playoff: Giants @ Nationals | ||
| 1 | Giants 7, Nationals 3 | WP: Fierson LP: Ronan |
| 2 | Nationals 10, Giants 0 | WP: Vielma LP: Seery |
| 3 | Nationals 6, Giants 0 | WP: Bezerro LP: Zuvella |
| 4 | Giants 8, Nationals 3 | WP: Seishisai LP: Pina |
| 5 | Giants 4, Nationals 1 | WP: Seery LP: Kuhl |
| Giants Win Series 3-2 | ||
| Second Round Playoff: Guardians @ Blue Jays | ||
| 1 | Blue Jays 5, Guardians 3 | WP: Meine LP: Wickman |
| 2 | Blue Jays 7, Guardians 2 | WP: Tokutomi LP: Vande Zandschulp |
| 3 | Guardians 11, Blue Jays 0 | WP: Barrameda LP: Smith II |
| 4 | Guardians 10, Blue Jays 4 | WP: Mattingly LP: Popinjay |
| 5 | Guardians 3, Blue Jays 2 | WP: Wickman LP: Muhammad |
| Guardians Win Series 3-2 | ||
| Second Round Playoff: Brewers @ Rockies | ||
| 1 | Rockies 5, Brewers 0 | WP: Hughes LP: Odeen |
| 2 | Rockies 5, Brewers 3 | WP: Kontos II LP: Hatmaker |
| 3 | Rockies 7, Brewers 6 | WP: Binette LP: McEnroe |
| Rockies Win Series 3-0 | ||
| Second Round Playoff: Angels @ Astros | ||
| 1 | Astros 13, Angels 4 | WP: Brown LP: Florimon |
| 2 | Astros 6, Angels 5 | WP: Dominquez LP: Porter |
| 3 | Astros 6, Angels 2 | WP: Sample LP: Anna |
| Astros Win Series 3-0 | ||
| Third Round Playoff: Giants @ Rockies | ||
| 1 | Giants 3, Rockies 2 | WP: Weyrauch LP: Cline |
| 2 | Rockies 6, Giants 3 | WP: Painter LP: Fierson |
| 3 | Giants 6, Rockies 2 | WP: Seery LP: Rock |
| 4 | Rockies 5, Giants 2 | WP: Houston LP: Brash |
| 5 | Rockies 5, Giants 0 | WP: Hughes LP: Zuvella |
| 6 | Rockies 5, Giants 2 | WP: Painter LP: Fierson |
| Rockies Win Series 4-2 | ||
| Third Round Playoff: Guardians @ Astros | ||
| 1 | Guardians 3, Astros 0 | WP: Vande Zandschulp LP: Brown |
| 2 | Astros 4, Guardians 0 | WP: Sturgeon LP: Barrameda |
| 3 | Guardians 6, Astros 0 | WP: Wickman LP: Sample |
| 4 | Guardians 12, Astros 6 | WP: Mattingly LP: Wonnum |
| 5 | Astros 6, Guardians 4 | WP: Pugh LP: Vande Zandschulp |
| 6 | Astros 6, Guardians 5 | WP: Nagelberg LP: Gi-Yong |
| 7 | Astros 7, Guardians 0 | WP: Sample LP: Wickman |
| Astros Win Series 4-3 | ||
| World Series: Rockies @ Astros | ||
| 1 | Astros 8, Rockies 1 | WP: Brown LP: Hughes |
| 2 | Rockies @ Astros | |
| 3 | Astros @ Rockies | |
| 4 | Astros @ Rockies | |
| 5 | Astros @ Rockies | |
| 6 | Rockies @ Astros | |
| 7 | Rockies @ Astros | |
| Astros Lead Series 1-0 | ||
