Playoff Series Breakdown
| Play-In Round: Indians @ Angels | ||
| 1 | Angels 7, Indians 0 | WP: Wise LP: Feller |
| 2 | Angels 3, Indians 1 | WP: Washburn LP: Allen |
| 3 | Indians 18, Angels 6 | WP: Harder LP: Ortiz |
| 4 | Angels 6, Indians 5 | WP: Shields LP: Galehouse |
| Angels Win Series 3-1 | ||
| Play-In Round: Nationals @ Astros | ||
| 1 | Astros 8, Nationals 2 | WP: McHugh LP: Nabholz |
| 2 | Astros 7, Nationals 1 | WP: Keuchel LP: Barnes |
| 3 | Astros 4, Nationals 1 | WP: McCullers LP: Martinez |
| Astros Win Series 3-0 | ||
| Play-In Round: Braves @ Dodgers | ||
| 1 | Braves 6, Dodgers 0 | WP: Jay LP: Erskine |
| 2 | Dodgers 4, Braves 1 | WP: Gregg LP: Pizarro |
| 3 | Dodgers 7, Braves 1 | WP: Lombardi LP: Spahn |
| 4 | Dodgers 6, Braves 1 | WP: Melton LP: Phillips |
| Dodgers Win Series 3-1 | ||
| Play-In Round: Reds @ Cardinals | ||
| 1 | Cardinals 3, Reds 2 | WP: Cooper LP: Cueto |
| 2 | Reds 8, Cardinals 1 | WP: Cingrani LP: White |
| 3 | Cardinals 5, Reds 1 | WP: Lanier LP: Bailey |
| 4 | Reds 5, Cardinals 2 | WP: Latos LP: Brecheen |
| 5 | Reds 1, Cardinals 0 | WP: Broxton LP: Hutchinson |
| Reds Win Series 3-2 | ||
| First Round Playoff: Reds @ Angels | ||
| 1 | Angels 6, Reds 3 | WP: Wise LP: Cingrani |
| 2 | Angels 4, Reds 0 | WP: Washburn LP: Bailey |
| 3 | Reds 7, Angels 0 | WP: Cueto LP: Ortiz |
| 4 | Angels 5, Reds 0 | WP: Escobar LP: Latos |
| Angels Win Series 3-1 | ||
| First Round Playoff: Astros @ Dodgers | ||
| 1 | Dodgers 3, Astros 1 | WP: Erskine LP: McHugh |
| 2 | Astros 5, Dodgers 2 | WP: Keuchel LP: Banta |
| 3 | Astros 4, Dodgers 3 | WP: Devenski LP: King |
| 4 | Astros 4, Dodgers 3 | WP: Richard LP: Melton |
| Astros Win Series 3-1 | ||
| First Round Playoff: Phillies @ Red Sox | ||
| 1 | Red Sox 2, Phillies 0 | WP: Butland LP: Rowe |
| 2 | Phillies 7, Red Sox 4 | WP: Church LP: Dobson |
| 3 | Red Sox 5, Phillies 3 | WP: Hughson LP: Simmons |
| 4 | Red Sox 9, Phillies 2 | WP: Fleming LP: Roberts |
| Red Sox Win Series 3-1 | ||
| First Round Playoff: Athletics @ Giants | ||
| 1 | Giants 5, Athletics 3 | WP: Grissom LP: Blue |
| 2 | Giants 4, Athletics 3 | WP: Wilhelm LP: Fingers |
| 3 | Giants 8, Athletics 7 | WP: Grissom LP: Nash |
| Giants Win Series 3-0 | ||
| Second Round Playoff: Astros @ Angels | ||
| 1 | Astros @ Angels | |
| 2 | Astros @ Angels | |
| 3 | Angels @ Astros | |
| 4 | Angels @ Astros | |
| 5 | Astros @ Angels | |
| Series Tied 0-0 | ||
| Second Round Playoff: Giants @ Red Sox | ||
| 1 | Giants @ Red Sox | |
| 2 | Giants @ Red Sox | |
| 3 | Red Sox @ Giants | |
| 4 | Red Sox @ Giants | |
| 5 | Giants @ Red Sox | |
| Series Tied 0-0 | ||
