| RP | Madson - Pirates, R.Madson - Pirates, Ryan | R | 92 | 1 | 2 | 2.13 | .235 | .260 | 0.97 | 6.7 | 2.0 | 8.3 | 63 | 47 | 5 | 14 | 58 | 0 | 3 | 1 | 23 | 18 | C |
| RP | Narveson - Angels, C.Narveson - Angels, Chris | L | 84 | 3 | 1 | 4.45 | .248 | .290 | 1.10 | 7.2 | 2.7 | 9.6 | 30 | 24 | 7 | 9 | 32 | 0 | 0 | 0 | 38 | 20 | C |
| RP | Aardsma - Phils, D.Aardsma - Phils, David | R | 27 | 2 | 2 | 4.31 | .314 | .350 | 1.49 | 9.0 | 4.4 | 8.3 | 39 | 39 | 7 | 19 | 36 | 0 | 0 | 1 | 23 | 19 | C |
| RP | Alburquerque - LAD, A.Alburquerque - LAD, Al | R | 48 | 4 | 3 | 4.59 | .317 | .350 | 1.49 | 7.2 | 6.2 | 12.9 | 49 | 39 | 5 | 34 | 70 | 0 | 0 | 9 | 23 | 24 | C |
| RP | Ambriz - FA, H.Ambriz - FA, Hector | R | 2 | 2 | 4 | 5.70 | .352 | .390 | 1.78 | 12.5 | 3.5 | 6.8 | 36 | 50 | 8 | 14 | 27 | 0 | 2 | 4 | 23 | 16 | C |
| RP | Bailey - Angels, A.Bailey - Angels, Andrew | R | 45 | 3 | 1 | 5.36 | .294 | .330 | 1.35 | 8.6 | 3.6 | 8.6 | 43 | 41 | 7 | 17 | 41 | 0 | 6 | 3 | 23 | 20 | C |
| RP | Beimel - O's, J.Beimel - O's, Joe | L | 62 | 3 | 1 | 2.20 | .268 | .300 | 1.18 | 7.8 | 2.8 | 5.0 | 45 | 39 | 4 | 14 | 25 | 0 | 0 | 3 | 23 | 15 | C |
| RP | Boyer - Yanks, B.Boyer - Yanks, Blaine | R | 78 | 0 | 1 | 3.57 | .244 | .280 | 1.05 | 7.7 | 1.8 | 6.5 | 40 | 34 | 2 | 8 | 29 | 0 | 0 | 1 | 25 | 17 | C |
| RP | Burke - FA, G.Burke - FA, Greg | R | 3 | 0 | 3 | 5.68 | .360 | .400 | 1.87 | 12.5 | 4.4 | 8.1 | 31 | 43 | 3 | 15 | 28 | 0 | 0 | 0 | 23 | 19 | C |
| RP | Carlyle - Reds, B.Carlyle - Reds, Buddy | R | 94 | 1 | 1 | 1.45 | .214 | .250 | 0.90 | 6.7 | 1.5 | 8.1 | 31 | 23 | 2 | 5 | 28 | 0 | 0 | 0 | 24 | 19 | C |
| RP | Carrasco - Astros, C.Carrasco - Astros, Carlos | R | 1 | 1 | 4 | 6.75 | .357 | .390 | 1.78 | 12.5 | 3.5 | 5.9 | 46 | 64 | 4 | 18 | 30 | 0 | 0 | 2 | 56 | 16 | C |
| RP | Cotts - Twins, N.Cotts - Twins, Neal | L | 96 | 8 | 3 | 1.11 | .230 | .260 | 0.95 | 5.7 | 2.8 | 10.3 | 57 | 36 | 2 | 18 | 65 | 0 | 1 | 3 | 23 | 20 | C |
| RP | Duke - Royals, Z.Duke - Royals, Zach | L | 80 | 5 | 1 | 2.45 | .264 | .290 | 1.14 | 7.6 | 2.6 | 11.5 | 58 | 49 | 3 | 17 | 74 | 0 | 0 | 3 | 23 | 22 | C |
| RP | Eveland - Cards, D.Eveland - Cards, Dana | L | 75 | 1 | 1 | 2.63 | .248 | .290 | 1.11 | 8.0 | 2.0 | 9.0 | 27 | 24 | 2 | 6 | 27 | 0 | 1 | 0 | 23 | 19 | C |
| RP | Guerrier - Nats, M.Guerrier - Nats, Matt | R | 26 | 4 | 4 | 4.01 | .306 | .340 | 1.43 | 9.2 | 3.6 | 6.4 | 42 | 43 | 3 | 17 | 30 | 0 | 0 | 0 | 23 | 17 | C |
| RP | Huff - Rox, D.Huff - Rox, David | L | 68 | 3 | 1 | 5.50 | .258 | .290 | 1.14 | 8.0 | 2.2 | 7.5 | 37 | 33 | 7 | 9 | 31 | 0 | 0 | 1 | 49 | 17 | C |
| RP | Masset - Phils, N.Masset - Phils, Nick | R | 5 | 2 | 0 | 5.80 | .356 | .390 | 1.78 | 11.2 | 4.8 | 7.2 | 45 | 56 | 3 | 24 | 36 | 0 | 0 | 2 | 23 | 17 | C |
| RP | Miner - FA, Z.Miner - FA, Zach | R | 3 | 0 | 2 | 4.40 | .347 | .390 | 1.79 | 10.6 | 5.5 | 6.4 | 28 | 33 | 4 | 17 | 20 | 0 | 0 | 1 | 34 | 16 | C |
| RP | Moylan - Reds, P.Moylan - Reds, Peter | R | 42 | 2 | 0 | 3.43 | .290 | .320 | 1.32 | 8.6 | 3.3 | 7.0 | 44 | 42 | 4 | 16 | 34 | 0 | 0 | 3 | 23 | 18 | C |
| RP | Neshek - Twins, P.Neshek - Twins, Pat | R | 33 | 2 | 1 | 3.35 | .297 | .330 | 1.38 | 9.0 | 3.4 | 6.5 | 40 | 40 | 6 | 15 | 29 | 0 | 0 | 1 | 23 | 17 | C |
| RP | Nunez - Astros, L.Nunez - Astros, Leo | R | 42 | 3 | 3 | 3.69 | .295 | .340 | 1.39 | 7.8 | 4.6 | 7.5 | 31 | 27 | 3 | 16 | 26 | 0 | 1 | 5 | 23 | 18 | C |
| RP | Penny - Cards, B.Penny - Cards, Brad | R | 1 | 2 | 1 | 6.58 | .348 | .400 | 1.81 | 11.8 | 4.5 | 4.5 | 26 | 34 | 3 | 13 | 13 | 0 | 0 | 2 | 59 | 16 | C |
| RP | Perez - Marlins, O.Perez - Marlins, Oliver | L | 40 | 3 | 3 | 3.74 | .310 | .340 | 1.43 | 8.5 | 4.4 | 12.6 | 53 | 50 | 6 | 26 | 74 | 0 | 2 | 1 | 23 | 24 | C |
| RP | Purcey - Astros, D.Purcey - Astros, David | L | 50 | 1 | 1 | 2.13 | .298 | .340 | 1.44 | 6.8 | 6.1 | 8.3 | 25 | 19 | 2 | 17 | 23 | 0 | 0 | 5 | 23 | 21 | C |
| RP | Qualls - A's, C.Qualls - A's, Chad | R | 56 | 5 | 2 | 2.61 | .279 | .310 | 1.23 | 8.3 | 2.8 | 7.1 | 62 | 57 | 4 | 19 | 49 | 0 | 0 | 1 | 23 | 18 | C |
| RP | Rivera - A's, M.Rivera - A's, Mariano | R | 76 | 6 | 2 | 2.11 | .249 | .280 | 1.05 | 8.2 | 1.3 | 7.6 | 64 | 58 | 6 | 9 | 54 | 0 | 44 | 0 | 23 | 17 | C |
| CL | Santos - Nats, S.Santos - Nats, Sergio | R | 99 | 1 | 1 | 1.75 | .150 | .190 | 0.60 | 4.0 | 1.4 | 10.1 | 25 | 11 | 1 | 4 | 28 | 0 | 1 | 1 | 23 | 24 | C |
| RP | Soria - Rangers, J.Soria - Rangers, Joakim | R | 85 | 2 | 4 | 3.25 | .237 | .270 | 1.00 | 7.8 | 1.2 | 9.8 | 44 | 38 | 2 | 6 | 48 | 0 | 18 | 1 | 23 | 22 | C |
| RP | Stauffer - Jays, T.Stauffer - Jays, Tim | R | 74 | 3 | 1 | 3.75 | .267 | .300 | 1.14 | 7.7 | 2.6 | 8.3 | 69 | 59 | 7 | 20 | 64 | 0 | 0 | 0 | 31 | 19 | C |
| RP | Troncoso - FA, R.Troncoso - FA, Ramon | R | 18 | 1 | 4 | 4.50 | .315 | .360 | 1.53 | 9.0 | 4.8 | 5.4 | 30 | 30 | 4 | 16 | 18 | 0 | 0 | 1 | 23 | 16 | C |
| RP | Valdes - FA, R.Valdes - FA, Raul | L | 25 | 1 | 1 | 7.46 | .303 | .340 | 1.43 | 10.8 | 2.1 | 9.5 | 35 | 42 | 7 | 8 | 37 | 0 | 0 | 1 | 39 | 22 | C |
| RP | Wang - Cubs, C.Wang - Cubs, Chien-Ming | R | 16 | 6 | 0 | 4.22 | .316 | .350 | 1.47 | 10.2 | 3.1 | 5.1 | 53 | 60 | 6 | 18 | 30 | 0 | 0 | 1 | 28 | 16 | C |
| RP | Wilson - Red Sox, B.Wilson - Red Sox, Brian | R | 22 | 2 | 4 | 4.66 | .336 | .370 | 1.63 | 9.2 | 5.4 | 10.1 | 48 | 49 | 5 | 29 | 54 | 0 | 1 | 1 | 23 | 20 | C |
| RP | Wood - Brewers, B.Wood - Brewers, Blake | R | 36 | 6 | 5 | 3.99 | .316 | .350 | 1.45 | 8.5 | 4.5 | 9.6 | 76 | 72 | 9 | 38 | 81 | 0 | 1 | 8 | 23 | 20 | C |