| C(1B) | Pierzynski, A.Pierzynski, A.J. >> | 34 | 2010 | L | 47 | 38 | 95 | 128 | .270 | .301 | .388 | .689 | .230 | 474 | 43 | 128 | 29 | 0 | 9 | 56 | 15 | 39 | 6 | 3 | .995 | - | +0.88 | 2 | 9 | 7 | C |
| 1B(OF) | Kotsay, M.Kotsay, Mark >> | 35 | 2010 | L | 23 | 27 | 35 | 107 | .239 | .306 | .376 | .682 | .240 | 327 | 30 | 78 | 17 | 2 | 8 | 31 | 32 | 36 | 0 | 1 | .997 | - | -0.91 | 3 | 9 | 6 | C |
| 1B(DH) | Konerko, P.Konerko, Paul >> | 34 | 2010 | R | 89 | 95 | 20 | 149 | .312 | .397 | .584 | .981 | .330 | 548 | 89 | 171 | 30 | 1 | 39 | 111 | 72 | 110 | 5 | 0 | .994 | - | -2.28 | 2 | 14 | 14 | C |
| 2B(IF) | Beckham, G.Beckham, Gordon >> | 24 | 2010 | R | 32 | 38 | 27 | 131 | .252 | .320 | .378 | .698 | .250 | 444 | 58 | 112 | 25 | 2 | 9 | 49 | 37 | 92 | 7 | 4 | .981 | - | -0.39 | 3 | 9 | 7 | C |
| 3B(2B) | Vizquel, O.Vizquel, Omar >> | 43 | 2010 | S | 54 | 55 | 38 | 108 | .276 | .345 | .331 | .676 | .280 | 344 | 36 | 95 | 11 | 1 | 2 | 30 | 34 | 45 | 2 | 11 | .987 | - | -0.34 | 5 | 7 | 6 | C |
| 3B(OF) | Teahen, M.Teahen, Mark >> | 29 | 2010 | L | 32 | 45 | 1 | 77 | .258 | .329 | .382 | .711 | .260 | 233 | 31 | 60 | 13 | 2 | 4 | 25 | 25 | 61 | 0 | 3 | .929 | - | -1.38 | 4 | 9 | 5 | C |
| SS(IF) | Ramirez, A.Ramirez, Alexei >> | 29 | 2010 | R | 60 | 55 | 86 | 156 | .282 | .316 | .431 | .747 | .250 | 585 | 83 | 165 | 29 | 2 | 18 | 70 | 27 | 82 | 2 | 13 | .974 | - | +3.01 | 4 | 10 | 29 | C |
| OF(OF) | Jones, A.Jones, Andruw >> | 33 | 2010 | R | 56 | 55 | 46 | 107 | .230 | .344 | .486 | .830 | .280 | 278 | 41 | 64 | 12 | 1 | 19 | 48 | 45 | 73 | 3 | 9 | .980 | - | +0.04 | 5 | 16 | 6 | C |
| OF(OF) | Pierre, J.Pierre, Juan >> | 33 | 2010 | L | 47 | 52 | 25 | 160 | .275 | .342 | .316 | .658 | .270 | 651 | 96 | 179 | 18 | 3 | 1 | 47 | 45 | 47 | 21 | 68 | .997 | - | -1.62 | 8 | 7 | 83 | C |
| OF(OF) | Quentin, C.Quentin, Carlos >> | 28 | 2010 | R | 46 | 59 | 1 | 131 | .243 | .344 | .479 | .823 | .280 | 453 | 73 | 110 | 25 | 2 | 26 | 87 | 50 | 83 | 20 | 2 | .959 | - | -3.11 | 2 | 13 | 7 | C |
| OF(OF) | Ramirez, M.Ramirez, Manny >> | 38 | 2010 | R | 82 | 91 | 1 | 90 | .298 | .413 | .460 | .873 | .350 | 265 | 38 | 79 | 16 | 0 | 9 | 42 | 46 | 61 | 6 | 1 | .959 | - | -1.45 | 2 | 11 | 5 | C |