| C(1B) | Varitek, J.Varitek, Jason >> | 36 | 2008 | S | 39 | 25 | 98 | 131 | .220 | .314 | .359 | .673 | .290 | 423 | 37 | 93 | 20 | 0 | 13 | 43 | 52 | 122 | 6 | 0 | .996 | - | +1.05 | 1 | 10 | 7 | C |
| 1B(3B) | Youkilis, K.Youkilis, Kevin >> | 29 | 2008 | R | 99 | 96 | 89 | 145 | .312 | .395 | .569 | .964 | .380 | 538 | 91 | 168 | 43 | 4 | 29 | 115 | 62 | 108 | 12 | 3 | .994 | - | +0.52 | 3 | 12 | 12 | C |
| 2B(IF) | Pedroia, D.Pedroia, Dustin >> | 25 | 2008 | R | 99 | 92 | 99 | 157 | .326 | .380 | .493 | .873 | .360 | 653 | 118 | 213 | 54 | 2 | 17 | 83 | 50 | 52 | 7 | 20 | .992 | - | +1.81 | 5 | 9 | 34 | C |
| 3B(DH) | Lowell, M.Lowell, Mike >> | 34 | 2008 | R | 70 | 67 | 70 | 113 | .274 | .342 | .461 | .803 | .320 | 419 | 58 | 115 | 27 | 0 | 17 | 73 | 38 | 61 | 5 | 2 | .967 | - | +0.86 | 2 | 11 | 5 | C |
| OF(OF) | Ellsbury, J.Ellsbury, Jacoby >> | 25 | 2008 | L | 72 | 60 | 99 | 145 | .280 | .337 | .394 | .731 | .320 | 554 | 98 | 155 | 22 | 7 | 9 | 47 | 41 | 80 | 7 | 50 | 1.000 | - | +1.03 | 8 | 8 | 12 | C |
| OF(OF) | Ramirez, M.Ramirez, Manny >> | 36 | 2008 | R | 91 | 98 | 11 | 153 | .332 | .432 | .601 | 1.033 | .410 | 552 | 102 | 183 | 36 | 1 | 37 | 121 | 87 | 124 | 11 | 3 | .985 | - | -1.25 | 2 | 14 | 20 | C |