| RP | Hoffman, T.Hoffman, Trevor + >> | 41 | 2006 | R | 50 | 0 | 2 | 2.14 | .263 | .320 | 1.13 | 8.0 | 2.1 | 5.3 | 63 | 56 | 6 | 15 | 37 | 0 | 46 | 2 | 20 | 15 | C |
| SP | Sanchez, A.Sanchez, Anibal >> | 24 | 2006 | R | 78 | 10 | 3 | 2.83 | .248 | .300 | 1.02 | 6.4 | 2.7 | 5.8 | 126 | 90 | 9 | 38 | 81 | 2 | 0 | 4 | 120 | 18 | C |
| SP | Morales, F.Morales, Franklin >> | 22 | 2007 | L | 70 | 3 | 2 | 3.43 | .253 | .320 | 1.09 | 7.0 | 2.9 | 7.2 | 44 | 34 | 2 | 14 | 35 | 0 | 0 | 0 | 92 | 17 | C |
| RP | Messenger, R.Messenger, Randy >> | 27 | 2005 | R | 59 | 0 | 0 | 5.35 | .273 | .340 | 1.20 | 7.0 | 3.8 | 9.9 | 50 | 39 | 5 | 21 | 55 | 0 | 0 | 1 | 32 | 20 | C |
| RP | Tucker, R.Tucker, Ryan >> | 22 | 2008 | R | 58 | 4 | 6 | 3.27 | .267 | .320 | 1.12 | 7.3 | 2.8 | 7.6 | 114 | 92 | 16 | 36 | 96 | 0 | 0 | 2 | 42 | 12 | C |
| RP | Petit, Y.Petit, Yusmeiro >> | 24 | 2008 | R | 63 | 3 | 5 | 4.31 | .249 | .310 | 1.05 | 7.2 | 2.3 | 6.8 | 56 | 45 | 12 | 14 | 42 | 0 | 0 | 3 | 54 | 17 | C |
| RP | Tankersley, T.Tankersley, Taylor >> | 25 | 2006 | L | 67 | 2 | 1 | 2.85 | .267 | .330 | 1.17 | 6.5 | 4.1 | 11.2 | 46 | 33 | 4 | 21 | 57 | 0 | 3 | 3 | 27 | 23 | C |
| SP | Peraza, O.Peraza, Oswaldo >> | 35 | 1988 | L | 66 | 9 | 8 | 4.07 | .257 | .310 | 1.05 | 7.6 | 1.9 | 7.3 | 202 | 171 | 28 | 42 | 164 | 8 | 0 | 12 | 108 | 15 | C |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 56 | 15 | 8 | 3.52 | .266 | .320 | 1.10 | 8.2 | 1.8 | 7.9 | 212 | 192 | 28 | 42 | 186 | 1 | 0 | 1 | 110 | 18 | C |
| SP | Johnson, J.Johnson, Josh >> | 24 | 2006 | R | 63 | 12 | 7 | 3.10 | .270 | .320 | 1.13 | 7.3 | 2.9 | 7.8 | 168 | 136 | 14 | 54 | 145 | 0 | 0 | 3 | 96 | 19 | C |
| SP | Olsen, S.Olsen, Scott >> | 24 | 2005 | L | 51 | 4 | 4 | 3.98 | .277 | .330 | 1.19 | 8.0 | 2.7 | 9.2 | 95 | 84 | 20 | 29 | 97 | 0 | 0 | 4 | 85 | 23 | C |
| RP | Resop, C.Resop, Chris >> | 26 | 2008 | R | 32 | 0 | 2 | 5.89 | .306 | .380 | 1.44 | 8.0 | 5.0 | 6.5 | 36 | 32 | 4 | 20 | 26 | 0 | 0 | 0 | 23 | 16 | C |
| RP | Nieve, F.Nieve, Fernando >> | 26 | 2006 | R | 54 | 3 | 3 | 4.20 | .268 | .320 | 1.13 | 7.5 | 2.7 | 6.9 | 105 | 87 | 18 | 32 | 81 | 0 | 0 | 1 | 49 | 19 | C |
| SP | Saarloos, K.Saarloos, Kirk >> | 27 | 2002 | R | 74 | 12 | 14 | 4.01 | .249 | .300 | 1.01 | 7.5 | 1.6 | 7.6 | 207 | 172 | 24 | 37 | 174 | 1 | 0 | 2 | 113 | 17 | C |
| SP | Vargas, J.Vargas, Jason >> | 25 | 2005 | L | 69 | 5 | 5 | 4.03 | .256 | .310 | 1.07 | 7.4 | 2.2 | 8.0 | 86 | 71 | 4 | 21 | 76 | 1 | 0 | 0 | 88 | 20 | C |
| SP | Dempster, R.Dempster, Ryan >> | 31 | 2000 | R | 57 | 14 | 10 | 3.66 | .273 | .330 | 1.14 | 7.6 | 2.7 | 8.5 | 250 | 210 | 30 | 76 | 236 | 2 | 0 | 4 | 138 | 23 | C |
| SP | Vanden Hurk, R.Vanden Hurk, Rick >> | 23 | 2007 | R | 12 | 4 | 6 | 6.83 | .337 | .400 | 1.58 | 9.6 | 4.6 | 9.3 | 88 | 94 | 15 | 45 | 91 | 0 | 0 | 4 | 82 | 20 | C |
| SP | Willis, D.Willis, Dontrelle >> | 26 | 2003 | L | 78 | 14 | 6 | 3.30 | .249 | .300 | 1.01 | 7.2 | 1.9 | 7.9 | 184 | 148 | 13 | 38 | 161 | 2 | 0 | 7 | 132 | 23 | C |
| SP | Volstad, C.Volstad, Chris >> | 22 | 2008 | R | 27 | 6 | 4 | 2.88 | .299 | .360 | 1.33 | 8.1 | 3.9 | 5.6 | 84 | 76 | 3 | 36 | 52 | 0 | 0 | 0 | 99 | 15 | C |