| C(DH) | Doumit, R.Doumit, Ryan >> | 27 | 2008 | S | 89 | 88 | 66 | 116 | .318 | .361 | .501 | .862 | .320 | 431 | 71 | 137 | 34 | 0 | 15 | 69 | 23 | 55 | 6 | 2 | .988 | - | +0.49 | 2 | +3.43 | 6 | C |
| C(DH) | Laird, G.Laird, Gerald >> | 29 | 2008 | R | 43 | 35 | 77 | 95 | .276 | .332 | .398 | .730 | .290 | 344 | 54 | 95 | 24 | 0 | 6 | 41 | 23 | 63 | 6 | 2 | .986 | - | +0.89 | 2 | +1.49 | 5 | C |
| 1B(3B) | Youkilis, K.Youkilis, Kevin >> | 29 | 2008 | R | 98 | 97 | 79 | 145 | .312 | .395 | .569 | .964 | .360 | 538 | 91 | 168 | 43 | 4 | 29 | 115 | 62 | 108 | 12 | 3 | .994 | - | +0.52 | 3 | +5.12 | 12 | C |
| 2B(IF) | Polanco, P.Polanco, Placido >> | 33 | 2008 | R | 81 | 71 | 91 | 141 | .307 | .353 | .417 | .770 | .310 | 580 | 90 | 178 | 34 | 3 | 8 | 58 | 35 | 43 | 6 | 7 | .989 | - | +1.75 | 4 | +2.98 | 10 | C |
| 2B(IF) | Matsui, K.Matsui, Kazuo >> | 33 | 2008 | S | 57 | 68 | 13 | 96 | .293 | .357 | .427 | .784 | .320 | 375 | 58 | 110 | 26 | 3 | 6 | 33 | 37 | 53 | 0 | 20 | .971 | - | -0.74 | 7 | +2.26 | 5 | C |
| 2B(SS) | Cabrera, A.Cabrera, Asdrubal >> | 23 | 2008 | S | 53 | 32 | 88 | 114 | .259 | .351 | .366 | .717 | .310 | 352 | 48 | 91 | 20 | 0 | 6 | 47 | 46 | 77 | 4 | 4 | .986 | - | +1.72 | 2 | +1.61 | 5 | C |
| 3B(IF) | Zimmerman, R.Zimmerman, Ryan >> | 24 | 2008 | R | 49 | 49 | 61 | 106 | .283 | .335 | .442 | .777 | .300 | 428 | 51 | 121 | 24 | 1 | 14 | 51 | 31 | 71 | 3 | 1 | .967 | - | +1.05 | 2 | +1.83 | 6 | C |
| SS(IF) | Tejada, M.Tejada, Miguel >> | 34 | 2008 | R | 38 | 33 | 82 | 158 | .283 | .316 | .415 | .731 | .280 | 632 | 92 | 179 | 38 | 3 | 13 | 66 | 24 | 72 | 6 | 7 | .983 | - | +1.3 | 3 | +1.33 | 42 | C |
| OF(OF) | Ellsbury, J.Ellsbury, Jacoby >> | 25 | 2008 | L | 55 | 41 | 98 | 145 | .280 | .337 | .394 | .731 | .300 | 554 | 98 | 155 | 22 | 7 | 9 | 47 | 41 | 80 | 7 | 50 | 1.000 | - | +1.03 | 8 | +1.72 | 12 | C |
| OF(OF) | Nady, X.Nady, Xavier # >> | 30 | 2008 | R | 82 | 85 | 46 | 148 | .305 | .360 | .510 | .870 | .320 | 555 | 76 | 169 | 37 | 1 | 25 | 97 | 39 | 103 | 9 | 2 | .987 | + | -0.16 | 2 | +2.98 | 14 | C |
| OF(OF) | Sweeney, R.Sweeney, Ryan >> | 23 | 2008 | L | 64 | 56 | 68 | 115 | .286 | .355 | .383 | .738 | .320 | 384 | 53 | 110 | 18 | 2 | 5 | 45 | 38 | 67 | 3 | 9 | .996 | - | -0.01 | 5 | +1.78 | 5 | C |