| C(1B) | McCann, B.McCann, Brian >> | 24 | 2008 | L | 96 | 91 | 92 | 145 | .301 | .375 | .523 | .898 | .340 | 509 | 68 | 153 | 42 | 1 | 23 | 87 | 57 | 64 | 4 | 5 | .991 | - | +1.57 | 2 | +4.68 | 12 | C |
| C(1B) | Rodriguez, I.Rodriguez, Ivan >> | 37 | 2008 | R | 39 | 29 | 90 | 115 | .276 | .321 | .394 | .715 | .280 | 398 | 44 | 110 | 20 | 3 | 7 | 35 | 23 | 67 | 3 | 10 | .993 | - | +1.08 | 5 | +1.27 | 5 | C |
| 1B(3B) | Barton, D.Barton, Daric >> | 23 | 2008 | L | 15 | 11 | 46 | 140 | .226 | .329 | .348 | .677 | .290 | 446 | 59 | 101 | 17 | 5 | 9 | 47 | 65 | 99 | 3 | 2 | .988 | - | -0.22 | 4 | +0.23 | 9 | C |
| 1B(DH) | Delgado, C.Delgado, Carlos >> | 36 | 2008 | L | 58 | 67 | 23 | 159 | .271 | .357 | .518 | .875 | .320 | 598 | 96 | 162 | 32 | 1 | 38 | 115 | 72 | 124 | 8 | 1 | .994 | - | -2.14 | 2 | +2.45 | 56 | C |
| 2B(IF) | Pedroia, D.Pedroia, Dustin >> | 25 | 2008 | R | 97 | 94 | 98 | 157 | .326 | .380 | .493 | .873 | .340 | 653 | 118 | 213 | 54 | 2 | 17 | 83 | 50 | 52 | 7 | 20 | .992 | - | +1.81 | 5 | +5.5 | 34 | C |
| 3B(DH) | Ramirez, A.Ramirez, Aramis >> | 30 | 2008 | R | 81 | 90 | 8 | 149 | .289 | .383 | .518 | .901 | .350 | 554 | 97 | 160 | 44 | 1 | 27 | 111 | 74 | 94 | 11 | 2 | .945 | - | -0.75 | 2 | +3.9 | 14 | C |
| SS(IF) | Betancourt, Y.Betancourt, Yuniesky >> | 26 | 2008 | R | 9 | 22 | 17 | 153 | .279 | .303 | .392 | .695 | .260 | 559 | 66 | 156 | 36 | 3 | 7 | 51 | 17 | 42 | 2 | 4 | .968 | - | -0.54 | 3 | +1.19 | 20 | C |
| OF(OF) | Ramirez, M.Ramirez, Manny >> | 36 | 2008 | R | 94 | 99 | 15 | 153 | .332 | .432 | .601 | 1.033 | .390 | 552 | 102 | 183 | 36 | 1 | 37 | 121 | 87 | 124 | 11 | 3 | .985 | - | -1.25 | 2 | +6.38 | 20 | C |
| OF(OF) | Granderson, C.Granderson, Curtis >> | 27 | 2008 | L | 71 | 75 | 37 | 141 | .280 | .365 | .494 | .859 | .330 | 553 | 112 | 155 | 26 | 13 | 22 | 66 | 71 | 111 | 3 | 12 | .989 | - | -0.62 | 7 | +4.78 | 10 | C |