| C(1B) | Varitek, J.Varitek, Jason >> | 36 | 2008 | S | 19 | 7 | 95 | 131 | .220 | .314 | .359 | .673 | .280 | 423 | 37 | 93 | 20 | 0 | 13 | 43 | 52 | 122 | 6 | 0 | .996 | - | +1.05 | 1 | +0.28 | 7 | C |
| C(DH) | Molina, B.Molina, Bengie >> | 34 | 2008 | R | 58 | 52 | 94 | 145 | .292 | .328 | .445 | .773 | .290 | 530 | 46 | 155 | 33 | 0 | 16 | 95 | 19 | 38 | 9 | 0 | .995 | - | +1.05 | 1 | +1.6 | 12 | C |
| 1B(DH) | Gonzalez, A.Gonzalez, Adrian >> | 26 | 2008 | L | 71 | 75 | 38 | 162 | .279 | .363 | .510 | .873 | .320 | 616 | 103 | 172 | 32 | 1 | 36 | 119 | 74 | 142 | 7 | 0 | .996 | - | -1.03 | 2 | +3.57 | 200 | C |
| 1B(DH) | LaRoche, A.LaRoche, Adam >> | 29 | 2008 | L | 47 | 57 | 28 | 136 | .270 | .345 | .500 | .845 | .310 | 492 | 66 | 133 | 32 | 3 | 25 | 85 | 54 | 122 | 2 | 1 | .993 | - | -1.37 | 3 | +1.85 | 8 | C |
| 2B(SS) | Cabrera, A.Cabrera, Asdrubal >> | 23 | 2008 | S | 53 | 32 | 88 | 114 | .259 | .351 | .366 | .717 | .310 | 352 | 48 | 91 | 20 | 0 | 6 | 47 | 46 | 77 | 4 | 4 | .986 | - | +1.72 | 2 | +1.61 | 5 | C |
| 3B(OF) | Wigginton, T.Wigginton, Ty >> | 31 | 2008 | R | 65 | 76 | 27 | 111 | .285 | .352 | .526 | .878 | .310 | 386 | 50 | 110 | 22 | 1 | 23 | 58 | 32 | 69 | 8 | 4 | .975 | - | -0.45 | 3 | +2.59 | 5 | C |
| 3B(DH) | Jones, C.Jones, Chipper † # >> | 36 | 2008 | S | 99 | 100 | 62 | 128 | .364 | .474 | .574 | 1.048 | .440 | 439 | 82 | 160 | 24 | 1 | 22 | 75 | 90 | 61 | 1 | 4 | .958 | - | +1.13 | 2 | +6.33 | 7 | C |
| SS(IF) | Guzman, C.Guzman, Cristian >> | 30 | 2008 | S | 75 | 73 | 79 | 138 | .316 | .348 | .440 | .788 | .310 | 579 | 77 | 183 | 35 | 5 | 9 | 55 | 23 | 57 | 5 | 6 | .972 | - | +1.82 | 4 | +3.37 | 9 | C |
| DH(OF) | Matsui, H.Matsui, Hideki >> | 34 | 2008 | L | 68 | 77 | 19 | 93 | .294 | .370 | .424 | .794 | .330 | 337 | 43 | 99 | 17 | 0 | 9 | 45 | 38 | 47 | 3 | 0 | .978 | - | -0.78 | 1 | +1.13 | 5 | C |
| OF(DH) | Beltran, C.Beltran, Carlos >> | 31 | 2008 | S | 95 | 84 | 99 | 161 | .284 | .379 | .500 | .879 | .340 | 606 | 116 | 172 | 40 | 5 | 27 | 112 | 92 | 96 | 1 | 25 | .993 | - | +1.99 | 6 | +5.24 | 164 | C |
| OF(DH) | Ordonez, M.Ordonez, Magglio >> | 34 | 2008 | R | 83 | 92 | 10 | 146 | .317 | .379 | .494 | .873 | .340 | 561 | 72 | 178 | 32 | 2 | 21 | 103 | 53 | 76 | 3 | 1 | .979 | - | -1.17 | 2 | +2.65 | 12 | C |
| OF(OF) | Hamilton, J.Hamilton, Josh >> | 27 | 2008 | L | 86 | 92 | 29 | 156 | .304 | .376 | .530 | .906 | .340 | 624 | 98 | 190 | 35 | 5 | 32 | 130 | 64 | 126 | 7 | 9 | .983 | - | -0.64 | 4 | +6.03 | 29 | C |