| C(1B) | Varitek, J.Varitek, Jason >> | 36 | 2008 | S | 19 | 7 | 95 | 131 | .220 | .314 | .359 | .673 | .280 | 423 | 37 | 93 | 20 | 0 | 13 | 43 | 52 | 122 | 6 | 0 | .996 | - | +1.05 | 1 | +0.28 | 7 | C |
| C(1B) | Molina, Y.Molina, Yadier >> | 26 | 2008 | R | 72 | 63 | 79 | 124 | .304 | .352 | .392 | .744 | .310 | 444 | 37 | 135 | 18 | 0 | 7 | 56 | 32 | 29 | 1 | 0 | .987 | - | +0.96 | 1 | +1.05 | 6 | C |
| 1B(DH) | Overbay, L.Overbay, Lyle >> | 31 | 2008 | L | 63 | 55 | 63 | 158 | .270 | .361 | .419 | .780 | .320 | 544 | 74 | 147 | 32 | 2 | 15 | 69 | 74 | 116 | 3 | 1 | .997 | - | -0.17 | 2 | +1.92 | 42 | C |
| 1B(DH) | Pujols, A.Pujols, Albert >> | 28 | 2008 | R | 100 | 100 | 91 | 148 | .357 | .468 | .653 | 1.121 | .430 | 524 | 100 | 187 | 44 | 0 | 37 | 116 | 104 | 54 | 5 | 7 | .996 | - | +0.9 | 2 | +7.42 | 14 | C |
| 3B(2B) | Stewart, I.Stewart, Ian >> | 23 | 2008 | L | 52 | 47 | 51 | 81 | .259 | .350 | .455 | .805 | .310 | 266 | 33 | 69 | 18 | 2 | 10 | 41 | 30 | 94 | 7 | 1 | .953 | - | +0.71 | 3 | +0.77 | 5 | C |
| 3B(DH) | Ramirez, A.Ramirez, Aramis >> | 30 | 2008 | R | 81 | 90 | 8 | 149 | .289 | .383 | .518 | .901 | .350 | 554 | 97 | 160 | 44 | 1 | 27 | 111 | 74 | 94 | 11 | 2 | .945 | - | -0.75 | 2 | +3.9 | 14 | C |
| SS(2B) | Scutaro, M.Scutaro, Marco >> | 33 | 2008 | R | 50 | 31 | 92 | 145 | .267 | .345 | .356 | .701 | .310 | 517 | 76 | 138 | 23 | 1 | 7 | 60 | 57 | 65 | 5 | 7 | .986 | - | +2.67 | 3 | +2.21 | 12 | C |
| OF(OF) | Markakis, N.Markakis, Nick >> | 25 | 2008 | L | 99 | 97 | 96 | 157 | .306 | .407 | .491 | .898 | .370 | 595 | 106 | 182 | 48 | 1 | 20 | 87 | 99 | 113 | 2 | 10 | .991 | + | +1.71 | 3 | +5.08 | 34 | C |
| OF(OF) | Dukes, E.Dukes, Elijah >> | 24 | 2008 | R | 74 | 74 | 35 | 81 | .264 | .389 | .478 | .867 | .350 | 276 | 48 | 73 | 16 | 2 | 13 | 44 | 50 | 79 | 6 | 13 | .965 | - | +0.02 | 7 | +1.92 | 5 | C |
| OF(OF) | Damon, J.Damon, Johnny >> | 35 | 2008 | L | 86 | 87 | 49 | 143 | .303 | .376 | .461 | .837 | .340 | 555 | 95 | 168 | 27 | 5 | 17 | 71 | 64 | 82 | 1 | 29 | .992 | - | -0.36 | 7 | +3.95 | 11 | C |