| C(DH) | Napoli, M.Napoli, Mike >> | 25 | 2006 | R | 52 | 38 | 78 | 99 | .228 | .361 | .455 | .816 | .320 | 268 | 47 | 61 | 13 | 0 | 16 | 42 | 51 | 90 | 5 | 2 | .987 | - | +0.74 | 2 | +2.35 | 6 | C |
| 1B(DH) | Helton, T.Helton, Todd >> | 33 | 2006 | L | 90 | 91 | 34 | 145 | .302 | .407 | .476 | .883 | .370 | 546 | 94 | 165 | 40 | 5 | 15 | 81 | 91 | 64 | 6 | 3 | .997 | - | -1.25 | 4 | +2.6 | 12 | C |
| 1B(OF) | Youkilis, K.Youkilis, Kevin >> | 27 | 2006 | R | 75 | 70 | 48 | 147 | .279 | .387 | .429 | .816 | .340 | 569 | 100 | 159 | 42 | 2 | 13 | 72 | 91 | 120 | 9 | 5 | .993 | - | -0.44 | 3 | +2.37 | 13 | C |
| 2B(1B) | Loretta, M.Loretta, Mark >> | 35 | 2006 | R | 42 | 37 | 54 | 155 | .285 | .348 | .361 | .709 | .310 | 635 | 75 | 181 | 33 | 0 | 5 | 59 | 49 | 63 | 12 | 4 | .994 | - | -0.4 | 2 | +1.2 | 25 | C |
| 3B(IF) | Zimmerman, R.Zimmerman, Ryan >> | 22 | 2006 | R | 51 | 63 | 38 | 157 | .287 | .353 | .471 | .824 | .310 | 614 | 84 | 176 | 47 | 3 | 20 | 110 | 61 | 120 | 2 | 11 | .965 | - | +0.11 | 4 | +2.96 | 34 | C |
| SS(DH) | Renteria, E.Renteria, Edgar >> | 31 | 2006 | R | 74 | 68 | 72 | 149 | .293 | .362 | .436 | .798 | .320 | 598 | 100 | 175 | 40 | 2 | 14 | 70 | 62 | 89 | 3 | 17 | .978 | - | +1.05 | 5 | +3.73 | 14 | C |
| OF(DH) | Bradley, M.Bradley, Milton >> | 28 | 2006 | S | 56 | 65 | 20 | 96 | .276 | .371 | .447 | .818 | .330 | 351 | 53 | 97 | 14 | 2 | 14 | 52 | 51 | 65 | 2 | 10 | .980 | - | -0.74 | 5 | +2.1 | 5 | C |
| OF(OF) | Cabrera, M.Cabrera, Melky >> | 22 | 2006 | S | 66 | 49 | 81 | 130 | .280 | .361 | .391 | .752 | .320 | 460 | 75 | 129 | 26 | 2 | 7 | 50 | 56 | 59 | 2 | 12 | .992 | - | +0.53 | 5 | +1.97 | 7 | C |
| OF(DH) | Catalanotto, F.Catalanotto, Frank # >> | 32 | 2006 | L | 79 | 80 | 41 | 128 | .300 | .379 | .439 | .818 | .340 | 437 | 56 | 131 | 36 | 2 | 7 | 56 | 52 | 37 | 4 | 1 | .993 | - | -0.65 | 2 | +1.86 | 7 | C |
| OF(OF) | Cameron, M.Cameron, Mike >> | 33 | 2006 | R | 55 | 56 | 56 | 141 | .268 | .358 | .482 | .840 | .320 | 552 | 88 | 148 | 34 | 9 | 22 | 83 | 71 | 142 | 6 | 25 | .984 | - | +0.25 | 7 | +4.32 | 10 | C |