| C(1B) | McCann, B.McCann, Brian >> | 22 | 2006 | L | 84 | 81 | 75 | 130 | .333 | .393 | .572 | .965 | .320 | 442 | 61 | 147 | 34 | 0 | 24 | 93 | 41 | 54 | 3 | 2 | .989 | - | +0.57 | 2 | +4.36 | 7 | C |
| C(DH) | Varitek, J.Varitek, Jason >> | 32 | 2004 | S | 64 | 42 | 94 | 137 | .296 | .391 | .482 | .873 | .310 | 463 | 67 | 137 | 30 | 1 | 18 | 73 | 62 | 126 | 10 | 10 | .998 | - | +0.85 | 4 | +3.91 | 8 | C |
| 1B(3B) | Youkilis, K.Youkilis, Kevin >> | 29 | 2008 | R | 81 | 74 | 81 | 145 | .312 | .395 | .569 | .964 | .320 | 538 | 91 | 168 | 43 | 4 | 29 | 115 | 62 | 108 | 12 | 3 | .994 | - | +0.52 | 3 | +5.12 | 12 | C |
| 1B(DH) | Fielder, P.Fielder, Prince >> | 25 | 2009 | L | 75 | 77 | 38 | 162 | .299 | .417 | .602 | 1.019 | .340 | 591 | 103 | 177 | 35 | 3 | 46 | 141 | 110 | 138 | 9 | 2 | .995 | - | -1.02 | 2 | +6.23 | 200 | C |
| 2B(DH) | Cano, R.Cano, Robinson >> | 24 | 2006 | L | 51 | 59 | 45 | 122 | .342 | .369 | .525 | .894 | .290 | 482 | 62 | 165 | 41 | 1 | 15 | 78 | 18 | 54 | 2 | 5 | .984 | - | -0.11 | 3 | +3.59 | 6 | C |
| 2B(OF) | Zobrist, B.Zobrist, Ben >> | 28 | 2009 | S | 82 | 65 | 96 | 152 | .297 | .407 | .543 | .950 | .330 | 501 | 91 | 149 | 28 | 7 | 27 | 91 | 91 | 104 | 2 | 17 | .987 | - | +2.55 | 7 | +6.1 | 18 | C |
| 3B(DH) | Cabrera, M.Cabrera, Miguel >> | 23 | 2006 | R | 83 | 93 | 8 | 158 | .339 | .433 | .568 | 1.001 | .360 | 576 | 112 | 195 | 50 | 2 | 26 | 114 | 86 | 108 | 10 | 9 | .957 | - | -0.79 | 4 | +6.72 | 42 | C |
| SS(IF) | Renteria, E.Renteria, Edgar # >> | 28 | 2003 | R | 70 | 69 | 57 | 157 | .330 | .398 | .480 | .878 | .320 | 587 | 96 | 194 | 47 | 1 | 13 | 100 | 65 | 54 | 1 | 34 | .975 | - | +0.62 | 7 | +5.63 | 34 | C |
| DH(OF) | Bradley, M.Bradley, Milton >> | 30 | 2008 | S | 81 | 90 | 11 | 126 | .321 | .441 | .563 | 1.004 | .370 | 414 | 78 | 133 | 32 | 1 | 22 | 77 | 80 | 112 | 9 | 5 | .940 | - | -0.55 | 3 | +4.7 | 6 | C |
| OF(DH) | Ordonez, M.Ordonez, Magglio >> | 33 | 2007 | R | 98 | 97 | 53 | 157 | .363 | .437 | .595 | 1.032 | .360 | 595 | 117 | 216 | 54 | 0 | 28 | 139 | 76 | 79 | 2 | 4 | .996 | - | -0.57 | 2 | +7.15 | 34 | C |
| OF(OF) | Markakis, N.Markakis, Nick >> | 25 | 2008 | L | 80 | 62 | 95 | 157 | .306 | .407 | .491 | .898 | .330 | 595 | 106 | 182 | 48 | 1 | 20 | 87 | 99 | 113 | 2 | 10 | .991 | + | +1.71 | 3 | +5.08 | 34 | C |
| OF(DH) | Sheffield, G.Sheffield, Gary >> | 32 | 2000 | R | 85 | 93 | 6 | 141 | .325 | .442 | .643 | 1.085 | .370 | 501 | 105 | 163 | 24 | 3 | 43 | 109 | 101 | 71 | 4 | 4 | .954 | - | -0.93 | 3 | +6.43 | 10 | C |