| C(1B) | Garver, M.Garver, Mitch >> | 30 | 2021 | R | 90 | 83 | 79 | 68 | .256 | .361 | .517 | .878 | .330 | 207 | 29 | 53 | 15 | 0 | 13 | 34 | 31 | 71 | 3 | 1 | .996 | - | +0.3 | 2 | +2.2 | 5 | C |
| C(1B) | Kirk, A.Kirk, Alejandro >> | 22 | 2021 | R | 63 | 57 | 66 | 60 | .242 | .332 | .436 | .768 | .300 | 165 | 19 | 40 | 8 | 0 | 8 | 24 | 19 | 22 | 3 | 0 | .995 | - | +0.1 | 1 | +1 | 5 | C |
| 2B(IF) | Altuve, J.Altuve, Jose >> | 31 | 2021 | R | 87 | 87 | 56 | 146 | .278 | .353 | .489 | .842 | .330 | 601 | 117 | 167 | 32 | 1 | 31 | 83 | 66 | 91 | 4 | 5 | .985 | - | +0.2 | 2 | +4.7 | 12 | C |
| 3B(2B) | McMahon, R.McMahon, Ryan >> | 26 | 2021 | L | 81 | 67 | 94 | 151 | .254 | .333 | .449 | .782 | .310 | 528 | 80 | 134 | 32 | 1 | 23 | 86 | 59 | 147 | 4 | 6 | .984 | - | +2.5 | 3 | +1.7 | 17 | C |
| 3B(IF) | Donaldson, J.Donaldson, Josh >> | 35 | 2021 | R | 74 | 75 | 32 | 135 | .247 | .357 | .475 | .832 | .330 | 457 | 73 | 113 | 26 | 0 | 26 | 72 | 74 | 114 | 4 | 0 | .952 | - | +0.1 | 1 | +3.1 | 8 | C |
| 3B(IF) | Machado, M.Machado, Manny >> | 28 | 2021 | R | 88 | 86 | 63 | 153 | .278 | .353 | .489 | .842 | .330 | 564 | 92 | 157 | 31 | 2 | 28 | 106 | 63 | 102 | 2 | 12 | .965 | - | +0.8 | 4 | +4.5 | 20 | C |
| SS(IF) | Adames, W.Adames, Willy >> | 25 | 2021 | R | 79 | 76 | 64 | 140 | .262 | .338 | .481 | .819 | .310 | 497 | 77 | 130 | 32 | 1 | 25 | 73 | 57 | 156 | 0 | 5 | .970 | - | +0.8 | 2 | +4.1 | 9 | C |
| SS(IF) | Anderson, T.Anderson, Tim >> | 28 | 2021 | R | 86 | 85 | 71 | 123 | .309 | .338 | .469 | .807 | .310 | 527 | 94 | 163 | 29 | 2 | 17 | 61 | 22 | 119 | 1 | 18 | .977 | - | +0.8 | 5 | +4.5 | 6 | C |
| OF(OF) | Nimmo, B.Nimmo, Brandon $$ >> | 28 | 2021 | L | 100 | 95 | 93 | 92 | .292 | .401 | .437 | .838 | .370 | 325 | 51 | 95 | 17 | 3 | 8 | 28 | 54 | 79 | 5 | 5 | .995 | - | +0.6 | 5 | +3.1 | 5 | C |
| OF(OF) | Taylor, T.Taylor, Tyrone >> | 27 | 2021 | R | 67 | 58 | 86 | 93 | .247 | .322 | .457 | .779 | .290 | 243 | 33 | 60 | 9 | 3 | 12 | 43 | 20 | 59 | 7 | 6 | 1.000 | - | +0.3 | 6 | +0.9 | 5 | C |
| OF(OF) | Mullins, C.Mullins, Cedric # >> | 26 | 2021 | S | 93 | 93 | 62 | 159 | .291 | .362 | .518 | .880 | .330 | 602 | 91 | 175 | 37 | 5 | 30 | 59 | 59 | 125 | 8 | 30 | .985 | - | +0.3 | 7 | +5.8 | 56 | C |
| OF(OF) | McCormick, C.McCormick, Chas >> | 26 | 2021 | R | 76 | 63 | 97 | 108 | .257 | .326 | .447 | .773 | .300 | 284 | 47 | 73 | 12 | 0 | 14 | 50 | 25 | 104 | 4 | 4 | .994 | - | +1.2 | 2 | +0.9 | 6 | C |