| C(1B) | Pierzynski, A.Pierzynski, A.J. >> | 34 | 2010 | L | 37 | 29 | 92 | 128 | .270 | .301 | .388 | .689 | .270 | 474 | 43 | 128 | 29 | 0 | 9 | 56 | 15 | 39 | 6 | 3 | .995 | - | +0.88 | 2 | +0.97 | 7 | C |
| 1B(DH) | Cabrera, M.Cabrera, Miguel >> | 27 | 2010 | R | 94 | 100 | 22 | 150 | .328 | .425 | .622 | 1.047 | .390 | 548 | 111 | 180 | 45 | 1 | 38 | 126 | 89 | 95 | 3 | 3 | .990 | - | -1.37 | 2 | +6.93 | 16 | C |
| 1B(DH) | Howard, R.Howard, Ryan >> | 31 | 2010 | L | 64 | 75 | 13 | 143 | .276 | .355 | .505 | .860 | .320 | 550 | 87 | 152 | 23 | 5 | 31 | 108 | 59 | 157 | 8 | 1 | .990 | - | -2.31 | 3 | +2.59 | 11 | C |
| 2B(IF) | Hudson, O.Hudson, Orlando >> | 33 | 2010 | S | 56 | 45 | 79 | 126 | .268 | .339 | .372 | .711 | .310 | 497 | 80 | 133 | 24 | 5 | 6 | 37 | 50 | 87 | 4 | 10 | .987 | - | +0.78 | 5 | +2.38 | 6 | C |
| 2B(SS) | Infante, O.Infante, Omar >> | 29 | 2010 | R | 82 | 79 | 62 | 134 | .321 | .360 | .416 | .776 | .330 | 471 | 65 | 151 | 15 | 3 | 8 | 47 | 29 | 62 | 0 | 7 | .967 | - | +0.92 | 4 | +2.32 | 8 | C |
| 3B(IF) | Beltre, A.Beltre, Adrian >> | 31 | 2010 | R | 95 | 94 | 77 | 154 | .321 | .369 | .553 | .922 | .340 | 589 | 84 | 189 | 49 | 2 | 28 | 102 | 40 | 82 | 5 | 2 | .957 | - | +2.37 | 2 | +5.73 | 22 | C |
| OF(OF) | Hunter, T.Hunter, Torii >> | 35 | 2010 | R | 68 | 72 | 27 | 152 | .281 | .357 | .464 | .821 | .320 | 573 | 76 | 161 | 36 | 0 | 23 | 90 | 61 | 106 | 7 | 9 | .992 | - | -1.15 | 3 | +4.14 | 18 | C |
| OF(OF) | Ramirez, M.Ramirez, Manny † # >> | 38 | 2010 | R | 85 | 94 | 4 | 90 | .298 | .413 | .460 | .873 | .380 | 265 | 38 | 79 | 16 | 0 | 9 | 42 | 46 | 61 | 6 | 1 | .959 | - | -1.45 | 2 | +1.78 | 5 | C |
| OF(OF) | Tabata, J.Tabata, Jose >> | 21 | 2010 | R | 62 | 64 | 39 | 102 | .299 | .347 | .400 | .747 | .310 | 405 | 61 | 121 | 21 | 4 | 4 | 35 | 28 | 57 | 2 | 19 | .995 | - | -0.85 | 7 | +1.23 | 6 | C |